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自我药疗与抗生素耐药性:危机、当前挑战及预防

Self-medication and antibiotic resistance: Crisis, current challenges, and prevention.

作者信息

Rather Irfan A, Kim Byung-Chun, Bajpai Vivek K, Park Yong-Ha

机构信息

Department of Applied Microbiology and Biotechnology, School of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk 38541, Republic of Korea.

Probionic Institute, Jeonju-si, Jeollabuk-do, Republic of Korea.

出版信息

Saudi J Biol Sci. 2017 May;24(4):808-812. doi: 10.1016/j.sjbs.2017.01.004. Epub 2017 Jan 9.

DOI:10.1016/j.sjbs.2017.01.004
PMID:28490950
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5415144/
Abstract

The present study aims to explore the crisis of antibiotic resistance and discover more about the current challenges related to self-medication. The current challenges related to antibiotic resistance are unique and differ from the challenges of the past since new bacterial pathogens are involved and continue to evolve. Strains with resistance to multiple antibiotic classes have emerged which the discovery of new antibiotics has failed to match. The consequences of antibiotic resistance are grave with mortality and morbidity continually on the rise. This paper also highlights the possible interventions that can be effective at the micro or individual level in the prevention of development of antibiotic resistance.

摘要

本研究旨在探讨抗生素耐药性危机,并进一步了解当前与自我药疗相关的挑战。当前与抗生素耐药性相关的挑战是独特的,与过去的挑战不同,因为涉及新的细菌病原体且它们在不断进化。已出现对多种抗生素类具有耐药性的菌株,而新抗生素的发现未能与之匹配。抗生素耐药性的后果严重,死亡率和发病率持续上升。本文还强调了在预防抗生素耐药性发展方面,在微观或个体层面可能有效的干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f42d/5415144/d0e24245856f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f42d/5415144/d0e24245856f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f42d/5415144/d0e24245856f/gr1.jpg

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Future Med Chem. 2016 Jun;8(10):1027-32. doi: 10.4155/fmc-2014-0032. Epub 2016 Jun 21.
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A systematic review of the public's knowledge and beliefs about antibiotic resistance.关于公众对抗生素耐药性的知识和看法的系统综述。
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