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[乳腺良性疾病的激素方面]

[Hormonal aspects of benign diseases of the breast].

作者信息

Görlich M

机构信息

Zentralinstitut für Krebsforschung, Akademie der Wissenschaften der DDR, Robert-Rössle-Institut, Berlin-Buch.

出版信息

Arch Geschwulstforsch. 1988;58(5):357-64.

PMID:2849385
Abstract

Basing on references from literature it has been looked for possibilities to characterize benign lesions of the breast by endocrine data and to find a discrimination between types connected with high or low risk for breast cancer. Conventional investigations of hormonal excretions and measurements of plasma contents only provide data for statistical evaluations which can not be used to assess the situation of an individual patient. Obviously one has to look for the processes of hormonal promotion on a cellular level. These processes are thought to realize a non-hormonal initial event to a benign or malignant disease. This requires finding of corresponding representative data. Some possibilities as receptor investigations or recording of hormone induced secretion proteins have been discussed.

摘要

基于文献参考,人们一直在探寻通过内分泌数据来表征乳腺良性病变的可能性,并找出与乳腺癌高风险或低风险相关类型之间的差异。传统的激素排泄研究和血浆含量测量仅提供用于统计评估的数据,而这些数据无法用于评估个体患者的情况。显然,必须在细胞水平上寻找激素促进的过程。这些过程被认为是良性或恶性疾病非激素初始事件的实现方式。这需要找到相应的代表性数据。已经讨论了一些可能性,如受体研究或激素诱导分泌蛋白的记录。

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