Tzingounis V, Cardamakis E, Ginopoulos P, Argiropoulos G
Department of Obstetrics and Gynecology, University of Patras, Rio, Greece.
Anticancer Res. 1996 Nov-Dec;16(6C):3997-4000.
The incidence of breast disorders, in a series of 142 women of reproductive age who received combined oral contraception (OC) for birth control and in 98 postmenopausal women who received hormone replacement therapy (HRT) with estrogens and progestins, for seven years, was compared with control groups. A lower incidence of benign breast diseases was observed among OC users (p < 0.001) and HRT recipients (p < 0.001). No differences were observed in the incidence of breast cancer among the groups studied. OC use and HRT do not increase the risk for breast cancer and decrease the incidence of benign breast diseases.
在142名接受复方口服避孕药(OC)用于避孕的育龄妇女以及98名接受雌激素和孕激素激素替代疗法(HRT)达七年的绝经后妇女中,将乳腺疾病的发病率与对照组进行了比较。观察到口服避孕药使用者(p < 0.001)和接受激素替代疗法者(p < 0.001)中良性乳腺疾病的发病率较低。在所研究的各组之间,乳腺癌发病率未观察到差异。使用口服避孕药和激素替代疗法不会增加患乳腺癌的风险,且会降低良性乳腺疾病的发病率。