Ryerson University, Toronto, Ontario, Canada.
Mount Saint Vincent University, Halifax, Nova Scotia, Canada.
J Atten Disord. 2020 Oct;24(12):1746-1756. doi: 10.1177/1087054717707297. Epub 2017 May 11.
Youth with ADHD and comorbid anxiety (ADHD+ANX) experience increased social and academic impairment compared with youth with ADHD without anxiety (ADHD). Group differences in attentional and impulse control may underlie this increased impairment. Examination of group differences using behavioral measures of attentional and impulse control has yielded inconsistent findings. This study explored group differences using event-related potentials (ERPs), which provide neural information concerning early information processing. ERPs (early frontal positivity [EFP], N2) were collected while youth aged 11 to 17 with ADHD ( = 31) and ADHD+ANX ( = 35) completed a visual and an auditory computer task. Compared with the ADHD group, the ADHD+ANX group exhibited larger N2 amplitudes to no-go stimuli and larger EFP amplitudes to target auditory stimuli, with variable attention allocation to nontarget stimuli. The addition of anxiety to ADHD appears to alter early attentional processing, which may be an important aspect of this comorbidity.
患有注意力缺陷多动障碍（ADHD）合并焦虑症（ADHD+ANX）的年轻人比单纯患有 ADHD 而没有焦虑症的年轻人在社交和学业方面受到更大的影响。注意力和冲动控制方面的群体差异可能是这种更大损害的基础。使用注意力和冲动控制的行为测量来检查群体差异，得到的结果并不一致。本研究使用事件相关电位（ERPs）来探索群体差异，ERPs 提供了与早期信息处理有关的神经信息。当 11 至 17 岁的 ADHD 儿童（n = 31）和 ADHD+ANX 儿童（n = 35）完成视觉和听觉计算机任务时，收集了他们的 ERPs（早期额叶正波 [EFP]，N2）。与 ADHD 组相比，ADHD+ANX 组对无反应刺激的 N2 振幅更大，对目标听觉刺激的 EFP 振幅更大，对非目标刺激的注意力分配也存在差异。ADHD 合并焦虑症似乎改变了早期注意力处理，这可能是这种合并症的一个重要方面。
