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心房颤动患者中风预防的新选择

New Stroke Prophylaxis Options in Atrial Fibrillation Patients.

作者信息

Thomas George, Lerman Bruce B

机构信息

Division of Cardiology, Cornell University Medical Center, New York Presbyterian Hospital, 520 E. 70th Street, Starr 4, New York, New York 10021.

出版信息

J Atr Fibrillation. 2013 Feb 12;5(5):462. doi: 10.4022/jafib.462. eCollection 2013 Feb-Mar.

DOI:10.4022/jafib.462
PMID:28496803
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5153098/
Abstract

Atrial Fibrillation (AF) is an epidemic that is increasing in size and scope. AF can have many symptoms and cause a variety of negative health impacts.The most important health risk of AF is the increased risk of stroke and systemic thromboembolism.Oral anticoagulation with warfarin has been the gold standard for stroke risk reduction in AF, but new drugs and treatment strategies for AF are changing clinical practice. These new advances could offer better tailoring of treatments to patients with high risk of stroke while reducing the potential bleeding complications.

摘要

心房颤动(AF)是一种规模和范围都在不断扩大的流行病。AF可能有多种症状,并会对健康造成各种负面影响。AF最重要的健康风险是中风和全身性血栓栓塞风险增加。使用华法林进行口服抗凝一直是降低AF中风风险的金标准,但AF的新药和治疗策略正在改变临床实践。这些新进展可以为中风高危患者提供更个性化的治疗,同时减少潜在的出血并发症。

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本文引用的文献

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Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects.在健康受试者中,用凝血酶原复合物浓缩物逆转利伐沙班和达比加群:一项随机、安慰剂对照、交叉研究。
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Validation of risk stratification schemes for predicting stroke and thromboembolism in patients with atrial fibrillation: nationwide cohort study.验证用于预测心房颤动患者中风和血栓栓塞风险分层方案的有效性:全国队列研究。
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An evaluation of the CHADS₂ stroke risk score in patients with atrial fibrillation who undergo percutaneous coronary revascularization.经皮冠状动脉血运重建术治疗的心房颤动患者中 CHADS₂ 卒中风险评分的评估。
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