基因组结构与毒力
The Genome Structure and Virulence.
作者信息
Gilchrist Carol A
机构信息
Department of Medicine, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America.
出版信息
Curr Trop Med Rep. 2016 Dec;3(4):158-163. doi: 10.1007/s40475-016-0088-9. Epub 2016 Oct 3.
Abstract
The outcome of an infection is variable and the contribution of genetic diversity within to human disease is not fully understood. The information provided by the whole genome sequence of the reference laboratory strain (HM-1:IMSS) and thirteen additional laboratory strains have been made publically available. In this review theories on the source of the unexpected level of structural diversity found in will be discussed.
摘要
感染的结果具有多样性，其内部遗传多样性对人类疾病的影响尚未完全明确。参考实验室菌株（HM-1:IMSS）及另外13种实验室菌株的全基因组序列所提供的信息已公开。在这篇综述中，将讨论关于在[具体名称未给出]中发现的意外高水平结构多样性来源的理论。
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