Muelleman Thomas, Shew Matthew, Subbarayan Rahul, Shum Axel, Sykes Kevin, Staecker Hinrich, Lin James
Department of Otolaryngology-Head and Neck Surgery, University of Kansas Medical Center, Kansas.
Otol Neurotol. 2017 Jul;38(6):870-875. doi: 10.1097/MAO.0000000000001429.
To compare the proportion of peripheral versus nonperipheral dizziness etiologies among all patients, inclusive of those presenting primarily or as referrals, to rank diagnoses in order of frequency, to determine whether or not age and sex predict diagnosis, and to determine which subgroups tended to undergo formal vestibular testing.
Retrospective cohort.
Academic neurotology clinic.
Age greater than 18 neurotology clinic patients with the chief complaint of dizziness.
INTERVENTION(S): None.
MAIN OUTCOME MEASURE(S): Age, sex, diagnosis, record of vestibular testing.
Two thousand seventy-nine patients were assigned 2,468 diagnoses, of which 57.7 and 42.3% were of peripheral and nonperipheral etiologies, respectively. The most common diagnoses were Ménière's (23.0%), vestibular migraine (19.3%), benign paroxysmal positional vertigo (BPPV) (19.1%), and central origin, nonmigraine (16.4%). Peripheral diagnoses are more likely to be found in men than in women (odds ratio [OR] 1.59). Peripheral diagnoses were most likely to be found in the 60 to 69 age group (OR 3.82). There was not a significant difference in rate of vestibular testing between women and men. Among patients with two diagnoses, the most common combinations were vestibular migraine and BPPV then vestibular migraine and Ménière's.
A large proportion of patients seen for the chief complaint of dizziness in the neurotology clinic were found not to have a peripheral etiology of their symptoms. These data challenge a prevalent dogma that the most common causes of dizziness are peripheral: BPPV, vestibular neuritis, and Ménière's disease. Age and sex are statistically significant predictors of peripheral etiology of dizziness.
比较所有患者(包括初诊患者和转诊患者)中周围性与非周围性头晕病因的比例,按频率对诊断进行排序,确定年龄和性别是否能预测诊断结果,并确定哪些亚组倾向于接受正式的前庭功能测试。
回顾性队列研究。
学术性耳神经科诊所。
年龄大于18岁、以头晕为主诉的耳神经科诊所患者。
无。
年龄、性别、诊断结果、前庭功能测试记录。
279例患者被诊断出2468种病症,其中分别有57.7%和42.3%为周围性和非周围性病因。最常见的诊断为梅尼埃病(23.0%)、前庭性偏头痛(19.3%)、良性阵发性位置性眩晕(BPPV,19.1%)和中枢性非偏头痛(16.4%)。男性比女性更易出现周围性诊断结果(优势比[OR]为1.59)。周围性诊断结果最常见于60至69岁年龄组(OR为3.82)。男性和女性在前庭功能测试率上无显著差异。在有两种诊断结果的患者中,最常见的组合是前庭性偏头痛合并BPPV,其次是前庭性偏头痛合并梅尼埃病。
在耳神经科诊所中,以头晕为主诉就诊的患者中,很大一部分被发现其症状并非由周围性病因引起。这些数据挑战了一种普遍的观点,即头晕最常见的原因是周围性的:BPPV、前庭神经炎和梅尼埃病。年龄和性别在统计学上是头晕周围性病因的显著预测因素。