Department of Chemistry, Ben-Gurion University of the Negev , Beer-Sheva 84105, Israel.
Org Lett. 2017 Jun 2;19(11):2917-2920. doi: 10.1021/acs.orglett.7b01152. Epub 2017 May 12.
Chiral iron phosphate complexes were successfully exploited for asymmetric cross-dehydrogenative coupling reactions between 2-naphthols and β-ketoester derivatives. On the basis of kinetic studies, it is suggested that iron monophosphate complexes constitute the active catalysts that induce stereoselectivity during the carbon-carbon bond-formation step.
手性磷酸铁配合物被成功应用于 2-萘酚和β-酮酯衍生物之间的不对称交叉脱氢偶联反应。基于动力学研究，建议单磷酸铁配合物构成了活性催化剂，在碳-碳键形成步骤中诱导立体选择性。
