Thompson A, Whyte A
Neurological Intervention and Imaging Service Western Australia, Level 1, G Block, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, WA 6009, Australia; Neurological Intervention and Imaging Service Western Australia, Royal Perth Hospital, 197 Wellington Street, Perth, WA 6000, Australia; Princess Margaret Hospital for Children, Roberts Road, Subiaco, WA 6008, Australia.
Perth Radiological Clinic, 127 Hamersley Road, Subiaco, WA 6008, Australia; School of Surgery, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia; Department of Medicine and Radiology, University of Melbourne, Parkville, VIC 3010, Australia.
Clin Radiol. 2018 Jan;73(1):106-120. doi: 10.1016/j.crad.2017.04.004. Epub 2017 May 10.
IgG4-related disease is a systemic, inflammatory disorder typically involving multiple organ systems. Several eponymous conditions described previously in the clinical and radiology literature are now recognised to be part of the IgG4-related disease spectrum. This includes multiple manifestations in the head and neck region, which are the subject of this review. Imaging can occasionally suggest the specific diagnosis of IgG4 disease. More commonly, it will be included in a limited differential diagnosis that requires clarification with the aid of image-guided biopsy. There are strict histopathological criteria for the diagnosis of IgG4-related disease.
IgG4相关性疾病是一种全身性炎症性疾病，通常累及多个器官系统。先前临床和放射学文献中描述的几种以人名命名的病症现在被认为是IgG4相关性疾病谱的一部分。这包括头颈部的多种表现，也是本综述的主题。影像学检查偶尔可提示IgG4疾病的明确诊断。更常见的情况是，它会被纳入一个有限的鉴别诊断范围，这需要借助影像引导下的活检来明确。IgG4相关性疾病的诊断有严格的组织病理学标准。
