Feo Leandro, Polcino Michael, Nash Garrett M
Colorectal Service, Department of Surgery, Catholic Medical Center, 100 McGregor Street, Suite 3100, Manchester, NH 03102, USA.
Division of Colorectal Surgery, St. Barnabas Hospital, 4422 Third Avenue, Bronx, NY 10457, USA.
Surg Clin North Am. 2017 Jun;97(3):657-669. doi: 10.1016/j.suc.2017.01.012.
Management of metastatic colorectal cancer requires accurate staging and multidisciplinary evaluation, leading to a consensus treatment plan with the ultimate goal of increasing survival and improving the quality of life, while taking into consideration the patient's performance status, disease burden, and goals of care. Since the introduction of multidrug chemotherapeutic regimens, survival of patients with metastatic colorectal cancer has improved. Many patients with unresectable disease are undergoing surgery for asymptomatic primary tumors despite evidence that it is usually a futile intervention. Palliative measures for local control of the primary tumor include colonic stents, laser therapy, and fulguration.
转移性结直肠癌的管理需要准确分期和多学科评估，从而达成共识的治疗方案，最终目标是提高生存率和改善生活质量，同时考虑患者的体能状态、疾病负担和护理目标。自从引入多药化疗方案以来，转移性结直肠癌患者的生存率有所提高。尽管有证据表明这通常是一种无效的干预措施，但许多无法切除的患者仍在接受针对无症状原发性肿瘤的手术。对原发性肿瘤进行局部控制的姑息治疗措施包括结肠支架置入、激光治疗和电灼术。
