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1
Vedolizumab: a novel medical intervention in the treatment of primary sclerosing cholangitis.维多珠单抗：治疗原发性硬化性胆管炎的一种新型医学干预措施。
BMJ Case Rep. 2017 May 13;2017:bcr-2017-220351. doi: 10.1136/bcr-2017-220351.
2
Cystic dilatation of intrahepatic bile ducts in primary sclerosing cholangitis.原发性硬化性胆管炎中肝内胆管的囊性扩张
J Hepatol. 1990 Sep;11(2):196-9. doi: 10.1016/0168-8278(90)90113-6.
3
Efficacy and safety of vedolizumab as a treatment option for moderate to severe refractory ulcerative colitis in two patients after liver transplant due to primary sclerosing cholangitis.维多珠单抗作为两名因原发性硬化性胆管炎行肝移植术后中重度难治性溃疡性结肠炎治疗选择的疗效及安全性
Rev Esp Enferm Dig. 2017 Sep;109(9):659-662. doi: 10.17235/reed.2017.5024/2017.
4
Management of Ulcerative Colitis Using Vedolizumab After Liver Transplantation for Primary Sclerosing Cholangitis.肝移植治疗原发性硬化性胆管炎后使用维多珠单抗治疗溃疡性结肠炎
J Crohns Colitis. 2016 Feb;10(2):236. doi: 10.1093/ecco-jcc/jjv182. Epub 2015 Oct 8.
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Vedolizumab Therapy is Ineffective for Primary Sclerosing Cholangitis in Patients With Inflammatory Bowel Disease: A GETAID Multicentre Cohort Study.Vedolizumab 治疗对炎症性肠病合并原发性硬化性胆管炎患者无效：GETAID 多中心队列研究。
J Crohns Colitis. 2019 Sep 27;13(10):1239-1247. doi: 10.1093/ecco-jcc/jjz088.
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Effects of vedolizumab, adalimumab and infliximab on biliary inflammation in individuals with primary sclerosing cholangitis and inflammatory bowel disease.维得利珠单抗、阿达木单抗和英夫利昔单抗对原发性硬化性胆管炎和炎症性肠病个体胆道炎症的影响。
Aliment Pharmacol Ther. 2018 Jul;48(2):190-195. doi: 10.1111/apt.14829. Epub 2018 May 28.
7
Effects of Vedolizumab in Patients With Primary Sclerosing Cholangitis and Inflammatory Bowel Diseases.维得利珠单抗治疗原发性硬化性胆管炎和炎症性肠病患者的效果。
Clin Gastroenterol Hepatol. 2020 Jan;18(1):179-187.e6. doi: 10.1016/j.cgh.2019.05.013. Epub 2019 May 14.
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Dysplasia and colorectal cancer in a patient with ulcerative colitis and primary sclerosing cholangitis: a case report and a short review of the literature.溃疡性结肠炎和原发性硬化性胆管炎患者的发育不良和结直肠癌：病例报告及文献复习。
J Crohns Colitis. 2013 Mar;7(2):e61-5. doi: 10.1016/j.crohns.2012.04.005. Epub 2012 Apr 30.
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Vedolizumab in patients with concurrent primary sclerosing cholangitis and inflammatory bowel disease does not improve liver biochemistry but is safe and effective for the bowel disease.维得利珠单抗治疗原发性硬化性胆管炎和炎症性肠病重叠患者时不会改善肝功能生化指标，但对肠病安全且有效。
Aliment Pharmacol Ther. 2018 Mar;47(6):753-762. doi: 10.1111/apt.14525. Epub 2018 Jan 29.
10
Return to sender: Lymphocyte trafficking mechanisms as contributors to primary sclerosing cholangitis.退回寄件人：淋巴细胞迁移机制是原发性硬化性胆管炎的致病因素之一。
J Hepatol. 2019 Sep;71(3):603-615. doi: 10.1016/j.jhep.2019.05.006. Epub 2019 May 18.

引用本文的文献

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An update on treatment options for primary sclerosing cholangitis.原发性硬化性胆管炎治疗方案的最新进展。
Gastroenterol Hepatol Bed Bench. 2020 Spring;13(2):115-124.
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The Use of Biologics in Patients with Inflammatory Bowel Disease and Primary Sclerosing Cholangitis.生物制剂在炎症性肠病和原发性硬化性胆管炎患者中的应用
Curr Hepatol Rep. 2019;18(1):115-126. doi: 10.1007/s11901-019-00456-2. Epub 2019 Mar 7.
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Comprehensive Review of Molecular Mechanisms during Cholestatic Liver Injury and Cholangiocarcinoma.胆汁淤积性肝损伤和胆管癌分子机制的综合综述
J Liver. 2018;7(3). doi: 10.4172/2167-0889.1000231. Epub 2018 Sep 20.

本文引用的文献

1
Primary Sclerosing Cholangitis.原发性硬化性胆管炎
N Engl J Med. 2016 Sep 22;375(12):1161-70. doi: 10.1056/NEJMra1506330.
2
Vedolizumab as induction and maintenance therapy for ulcerative colitis.维得利珠单抗用于溃疡性结肠炎的诱导缓解和维持治疗。
N Engl J Med. 2013 Aug 22;369(8):699-710. doi: 10.1056/NEJMoa1215734.
3
The burden of large and small duct primary sclerosing cholangitis in adults and children: a population-based analysis.成人和儿童大小胆管原发性硬化性胆管炎的负担：基于人群的分析。
Am J Gastroenterol. 2007 May;102(5):1042-9. doi: 10.1111/j.1572-0241.2007.01103.x. Epub 2007 Feb 21.

Vedolizumab: a novel medical intervention in the treatment of primary sclerosing cholangitis.

作者信息

Westerveld Donevan, Grajo Joseph, Beattie Lars, Glover Sarah

机构信息

Department of Internal Medicine, University of Florida, Gainesville, Florida, USA.

Department of Radiology, University of Florida College of Medicine, Gainesville, Florida, USA.

出版信息

BMJ Case Rep. 2017 May 13;2017:bcr-2017-220351. doi: 10.1136/bcr-2017-220351.

DOI:10.1136/bcr-2017-220351
PMID:28501828
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5614261/
Abstract
摘要