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Topically Delivered Tumor Necrosis Factor-α-Targeted Gene Regulation for Psoriasis.

作者信息

Lewandowski Katherine T, Thiede Rebecca, Guido Nicholas, Daniel Weston L, Kang Richard, Guerrero-Zayas Mara-Isel, Seeger Mark A, Wang Xiao-Qi, Giljohann David A, Paller Amy S

机构信息

Department of Dermatology, Northwestern University, Chicago, Illinois, USA.

Exicure, Incorporated, Skokie, Illinois, USA.

出版信息

J Invest Dermatol. 2017 Sep;137(9):2027-2030. doi: 10.1016/j.jid.2017.04.027. Epub 2017 May 11.

DOI:10.1016/j.jid.2017.04.027
PMID:28502802
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8405255/
Abstract
摘要

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Topically Delivered Tumor Necrosis Factor-α-Targeted Gene Regulation for Psoriasis.局部递送肿瘤坏死因子-α靶向基因调控治疗银屑病
J Invest Dermatol. 2017 Sep;137(9):2027-2030. doi: 10.1016/j.jid.2017.04.027. Epub 2017 May 11.
2
Response to tumor necrosis factor in two cases of psoriasis.两例银屑病对肿瘤坏死因子的反应
J Am Acad Dermatol. 1991 May;24(5 Pt 1):735-7. doi: 10.1016/0190-9622(91)70112-f.
3
Psoriasis induced by anti-tumor necrosis factor therapy: a class effect?抗肿瘤坏死因子治疗诱发的银屑病：一种类效应？
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4
A TNF-alpha promoter polymorphism is associated with juvenile onset psoriasis and psoriatic arthritis.肿瘤坏死因子-α启动子多态性与青少年银屑病和银屑病关节炎相关。
J Invest Dermatol. 1997 Oct;109(4):562-5. doi: 10.1111/1523-1747.ep12337469.
5
[TNF alpha in the physiopathology of psoriasis].[肿瘤坏死因子α在银屑病病理生理学中的作用]
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Tumor necrosis factor-alpha in psoriasis and psoriatic arthritis: a clinical, genetic, and histopathologic perspective.银屑病和银屑病关节炎中的肿瘤坏死因子-α：临床、遗传学及组织病理学视角
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Involvement of TNF-α converting enzyme in the development of psoriasis-like lesions in a mouse model.肿瘤坏死因子-α转化酶在小鼠模型银屑病样皮损形成中的作用
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Different transcriptional activity and in vitro TNF-alpha production in psoriasis patients carrying the TNF-alpha 238A promoter polymorphism.携带肿瘤坏死因子-α 238A启动子多态性的银屑病患者具有不同的转录活性和体外肿瘤坏死因子-α产生情况。
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Promoter polymorphism at -238 of the tumor necrosis factor alpha gene is not associated with early onset psoriasis when tested by the transmission disequilibrium test.通过传递不平衡检验进行检测时，肿瘤坏死因子α基因-238位点的启动子多态性与早发型银屑病无关。
J Invest Dermatol. 1999 Apr;112(4):514-6. doi: 10.1046/j.1523-1747.1999.00541.x.

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本文引用的文献

1
The Snowballing Literature on Imiquimod-Induced Skin Inflammation in Mice: A Critical Appraisal.关于咪喹莫特诱导小鼠皮肤炎症的文献综述：批判性评价
J Invest Dermatol. 2017 Mar;137(3):546-549. doi: 10.1016/j.jid.2016.10.024. Epub 2016 Dec 9.
2
The immunogenetics of Psoriasis: A comprehensive review.银屑病的免疫遗传学：全面综述。
J Autoimmun. 2015 Nov;64:66-73. doi: 10.1016/j.jaut.2015.07.008. Epub 2015 Jul 26.
3
siRNA-based spherical nucleic acids reverse impaired wound healing in diabetic mice by ganglioside GM3 synthase knockdown.基于小干扰RNA的球形核酸通过敲低神经节苷脂GM3合酶逆转糖尿病小鼠受损的伤口愈合。
Proc Natl Acad Sci U S A. 2015 May 5;112(18):5573-8. doi: 10.1073/pnas.1505951112. Epub 2015 Apr 20.
4
Liposomal spherical nucleic acids.脂质体球形核酸
J Am Chem Soc. 2014 Jul 16;136(28):9866-9. doi: 10.1021/ja504845f. Epub 2014 Jul 1.
5
Immunology of psoriasis.银屑病的免疫学
Annu Rev Immunol. 2014;32:227-55. doi: 10.1146/annurev-immunol-032713-120225.
6
Mechanism for the endocytosis of spherical nucleic acid nanoparticle conjugates.球形核酸纳米颗粒缀合物内吞作用的机制。
Proc Natl Acad Sci U S A. 2013 May 7;110(19):7625-30. doi: 10.1073/pnas.1305804110. Epub 2013 Apr 23.
7
Topical delivery of siRNA-based spherical nucleic acid nanoparticle conjugates for gene regulation.基于球形核酸纳米粒子缀合物的 siRNA 的局部递送来进行基因调控。
Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):11975-80. doi: 10.1073/pnas.1118425109. Epub 2012 Jul 6.
8
Spherical nucleic acids.球形核酸。
J Am Chem Soc. 2012 Jan 25;134(3):1376-91. doi: 10.1021/ja209351u. Epub 2012 Jan 9.
9
Integrative responses to IL-17 and TNF-α in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis.人角质形成细胞对白细胞介素-17 和肿瘤坏死因子-α 的整合反应解释了银屑病中关键的炎症发病机制。
J Invest Dermatol. 2011 Mar;131(3):677-87. doi: 10.1038/jid.2010.340. Epub 2010 Nov 18.
10
Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis.咪喹莫特诱导的小鼠银屑病样皮肤炎症是通过白细胞介素-23/白细胞介素-17轴介导的。
J Immunol. 2009 May 1;182(9):5836-45. doi: 10.4049/jimmunol.0802999.