Bacić G, Walczak T, Demsar F, Swartz H M
College of Medicine, University of Illinois, Urbana 61801.
Magn Reson Med. 1988 Oct;8(2):209-19. doi: 10.1002/mrm.1910080211.
Electron spin resonance imaging and spectroscopy of lipid-rich samples were studied at 9 Ghz. Using both lipid- and aqueous-soluble nitroxides good delineation of fat- and muscle-rich regions of tissue was obtained. Several different principles can be used to differentiate between these types of tissues and potentially between different types of lipids. These principles include lipophilicity of nitroxides, viscosity (which is higher in lipids), oxygen solubility (oxygen is four times more soluble in lipids), and the distribution of paramagnetic metal ions. These techniques have potential applicability for directly studying metabolism and oxygen concentration in tissues by ESR techniques and for investigating potential contrast agents for in vivo NMR techniques.
在9吉赫兹频率下研究了富含脂质样品的电子自旋共振成像和光谱学。使用脂溶性和水溶性氮氧化物均能很好地勾勒出组织中富含脂肪和肌肉的区域。可以使用几种不同的原理来区分这些类型的组织，甚至可能区分不同类型的脂质。这些原理包括氮氧化物的亲脂性、粘度（脂质中的粘度更高）、氧溶解度（氧在脂质中的溶解度高四倍）和顺磁性金属离子的分布。这些技术在通过电子自旋共振技术直接研究组织中的代谢和氧浓度以及研究体内核磁共振技术的潜在造影剂方面具有潜在的适用性。
