Department of Infectious Diseases, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.
Department of Infectious Diseases, Central Hospital of Xianyang City, Shaanxi Province, Xianyang, Shaanxi, P. R. China.
J Med Virol. 2017 Oct;89(10):1865-1870. doi: 10.1002/jmv.24856. Epub 2017 Jun 6.
Hantavirus infection during pregnancy can influence both maternal and fetal outcomes. Here, we describe four cases of hemorrhagic fever with renal syndrome (HFRS) in pregnant Chinese women. The HFRS put these women at increased risk for severe illness, despite the patients' symptomologies in the onset phase were similar to those observed in non-pregnant HFRS patients, such as fever, headache, nausea, and thrombocytopenia. Pregnant women appeared to have a more severe status, presenting with severe complications, such as hypervolemia and pulmonary edema. Nevertheless, with appropriate management, mothers with HFRS may carry to full-term and breastfeeding maybe safe and feasible.
汉坦病毒感染孕妇可影响母婴结局。本研究描述了 4 例中国妊娠女性肾综合征出血热（HFRS）。尽管 HFRS 患者的首发症状与非妊娠 HFRS 患者相似，如发热、头痛、恶心和血小板减少症，但 HFRS 使这些女性罹患重症的风险增加。孕妇的病情似乎更严重，出现严重并发症，如血容量过多和肺水肿。然而，通过适当的治疗，HFRS 母亲可以足月分娩，母乳喂养可能是安全可行的。
