Donini Lorenzo Maria, Rosano Aldo, Di Lazzaro Luca, Poggiogalle Eleonora, Lubrano Carla, Migliaccio Silvia, Carbonelli Mariagrazia, Pinto Alessandro, Lenzi Andrea
High Specialization Centre for the Care of Obesity ("CASCO"), Department of Experimental Medicine, Medical Pathophysiology, Food Science and Endocrinology Section, "Sapienza" University of Rome, Rome, Italy.
"Sapienza" University of Rome, Department of Experimental Medicine- Medical Pathophysiology, Food Science and Endocrinology Section, Food Science and Human Research Unit, p.le Aldo Moro n.5, 00185, Rome, Italy.
Health Qual Life Outcomes. 2017 May 15;15(1):101. doi: 10.1186/s12955-017-0671-3.
Obesity is associated to increased risk of metabolic comorbidity as well as increased mortality. Notably, obesity is also associated to the impairment of the psychological status and of quality of life. Only three questionnaires are available in the Italian language evaluating the health-related quality of life in subjects with obesity. The aim of the present study was to test the validity and reliability of the Italian version of the Laval Questionnaire.
The original French version was translated into Italian and back-translated by a French native speaker. 273 subjects with obesity (Body Mass Index ≥ 30 kg/m) were enrolled; the Italian version of the Laval Questionnaire and the O.R.Well-97 questionnaire were administered in order to assess health- related quality of life. The Laval questionnaire consists of 44 items distributed in 6 domains (symptoms, activity/mobility, personal hygiene/clothing, emotions, social interaction, sexual life). Disability and overall psychopathology levels were assessed through the TSD-OC test (SIO test for obesity correlated disabilities) and the SCL-90 (Symptom Checklist-90) questionnaire, respectively. To verify the validity of the Italian version, the analysis of internal consistency, test-retest reliability, and construct validity were performed.
The observed proportion of agreement concordance of results was 50.2% with Cohen's K = 0.336 (CI 95%: 0.267-0.404), indicating a fair agreement between the two tests. Test-retest correlation was statistically significant (ρ = 0.82; p < 0.01); validity (standardized Chronbach's alpha) was considered reliable (α > 0.70). The analysis of construct validity showed a statistically significant association in terms of both total score (ρ = -0.66) and scores at each single domain (p < 0.01). A high correlation (p < 0.01) was observed between Laval questionnaire total and single domain scores and other related measures (Body Mass Index, TSD-OC scores, SCL-90 global severity index), revealing a high construct validity of the test.
The Italian version of the Laval Questionnaire is a valid and reliable measure to assess the health-related quality of life in subjects with obesity.
肥胖与代谢合并症风险增加以及死亡率上升相关。值得注意的是，肥胖还与心理状态和生活质量受损有关。在意大利语中，仅有三份问卷可用于评估肥胖受试者的健康相关生活质量。本研究的目的是检验意大利版拉瓦尔问卷的有效性和可靠性。
将原始法语版本翻译成意大利语，并由一位以法语为母语的人士进行回译。招募了273名肥胖受试者（体重指数≥30kg/m²）；发放意大利版拉瓦尔问卷和O.R.Well-97问卷以评估健康相关生活质量。拉瓦尔问卷由44个项目组成，分布在6个领域（症状、活动/ mobility、个人卫生/服装、情绪、社交互动、性生活）。分别通过TSD-OC测试（肥胖相关残疾的SIO测试）和SCL-90（症状自评量表-90）问卷评估残疾程度和总体精神病理学水平。为验证意大利版的有效性，进行了内部一致性分析、重测信度分析和结构效度分析。
结果的一致性观察比例为50.2%，Cohen's K = 0.336（95%置信区间：0.267 - 0.404），表明两项测试之间一致性尚可。重测相关性具有统计学意义（ρ = 0.82；p < 0.01）；效度（标准化克朗巴哈系数）被认为可靠（α > 0.70）。结构效度分析显示，总分（ρ = -0.66）和每个单一领域的得分（p < 0.01）均具有统计学意义的关联。拉瓦尔问卷总分及单一领域得分与其他相关指标（体重指数、TSD-OC得分、SCL-90总体严重程度指数）之间观察到高度相关性（p < 0.01），表明该测试具有较高的结构效度。
意大利版拉瓦尔问卷是评估肥胖受试者健康相关生活质量的有效且可靠的工具。
