Torbenson Michael S
Department of Laboratory Medicine and Pathology, Mayo Clinic Rochester, Rochester, MN, USA.
Gastroenterol Clin North Am. 2017 Jun;46(2):365-391. doi: 10.1016/j.gtc.2017.01.009.
Hepatocellular carcinomas can be further divided into distinct subtypes that provide important clinical information and biological insights. These subtypes are distinct from growth patterns and are on based on morphologic and molecular findings. There are 12 reasonably well-defined subtypes as well as 6 provisional subtypes, together making up 35% of all hepatocellular carcinomas. These subtypes are discussed, with an emphasis on their definitions and the key morphologic findings.
肝细胞癌可进一步分为不同的亚型，这些亚型能提供重要的临床信息和生物学见解。这些亚型不同于生长模式，是基于形态学和分子学发现划分的。有12种定义较为明确的亚型以及6种暂定亚型，它们共占所有肝细胞癌的35%。本文将对这些亚型进行讨论，重点是它们的定义和关键形态学发现。
