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骶骨阴道固定术和耻骨后吊带术对膀胱过度活动症症状的影响。

Effect of sacrocolpopexy and retropubic sling on overactive bladder symptoms.

作者信息

Aslam Muhammad Faisal, Gregory William T, Osmundsen Blake

机构信息

Department of Obstetrics and Gynecology, St. John Hospital and Medical Center, Detroit, MI, USA.

Department of Obstetrics and Gynecology, Oregon Health&Science University, Portland, OR, USA.

出版信息

J Turk Ger Gynecol Assoc. 2017 Mar 15;18(1):9-14. doi: 10.4274/jtgga.2016.0176.

Abstract

OBJECTIVE

In this study, we aimed to evaluate the effect of sacrocolpopexy and retropubic midurethral sling, or transvaginal tape (TVT) procedure, on overactive bladder (OAB) symptoms. Our null hypothesis was that concomitant sacrocolpopexy and TVT exacerbate OAB symptoms.

MATERIAL AND METHODS

This is a prospective cohort study. All subjects had apical/anterior prolapse and underwent robotic-assisted sacrocolpopexy and TVT, with or without concomitant hysterectomy. All subjects completed a standardized one-year follow-up between 2009 and 2014. To assess for OAB symptoms, we used the Urogenital Distress Inventory subscale questions #15 and/or question #16. Reponses to these questions are based on a five-point 0 to 4 Likert scale (0 represents a negative response or no symptoms, and 4 represents the most problems). Any patient who answered 1 or higher on the Likert scale, either on the frequency or urge incontinence question, was defined as having OAB symptoms.

RESULTS

Sixty-six subjects completed 12 months of visits. Preoperatively, 54 patients (83%) had OAB symptoms, and postoperatively 29 patients (45%) had OAB symptoms (p<0.001). Patients with postoperative OAB had a lower patient global impression of improvement (PGI-I) scores, PGI-I 5.8 with OAB, and PGI-I 6.6 without OAB (p<0.003).

CONCLUSION

We found that sacrocolpopexy and concomitant retropubic midurethral sling does not contribute to additive OAB symptoms, and symptoms actually resolved in 38% of women in our cohort. The presence of postoperative OAB contributes to lower global impression of improvement.

摘要

目的

在本研究中,我们旨在评估骶骨阴道固定术联合耻骨后中段尿道吊带术或经阴道无张力尿道中段吊带术(TVT)对膀胱过度活动症(OAB)症状的影响。我们的零假设是,骶骨阴道固定术与TVT联合使用会加重OAB症状。

材料与方法

这是一项前瞻性队列研究。所有受试者均有顶端/前部脱垂,并接受了机器人辅助的骶骨阴道固定术和TVT,部分患者还同时进行了子宫切除术。所有受试者在2009年至2014年间完成了为期一年的标准化随访。为评估OAB症状,我们使用了泌尿生殖系统困扰量表第15题和/或第16题。对这些问题的回答基于0至4分的五点李克特量表(0表示无不良反应或无症状,4表示问题最多)。在频率或急迫性尿失禁问题上,任何在李克特量表上回答为1或更高的患者都被定义为有OAB症状。

结果

66名受试者完成了12个月的随访。术前,54名患者(83%)有OAB症状,术后29名患者(45%)有OAB症状(p<0.001)。术后有OAB症状的患者的患者总体改善印象(PGI-I)得分较低,有OAB症状的患者PGI-I为5.8,无OAB症状的患者PGI-I为6.6(p<0.003)。

结论

我们发现,骶骨阴道固定术联合耻骨后中段尿道吊带术不会加重OAB症状,实际上,我们队列中38%的女性症状得到了缓解。术后出现OAB症状会导致总体改善印象较低。

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