Ahmed Asif, Jehan Farhat
Department of Pharmacology, Baqai Medical University, Karachi, Pakistan.
Department of Community Medicines, Baqai Medical University, Karachi, Pakistan.
J Pak Med Assoc. 2017 May;67(5):785-787.
The main objective of the current study is to evaluate the medicinal role of Papaya seeds on thrombocyte count and hepatic parameter on healthy rabbits. Experimental and Interventional study, at the Department of pharmacology Baqai Medical University Karachi. Rabbits (18 in number different age and both sex) were included, subsequently subdivided into three group (n=6). Group A (Control), B and C (sample fed dose 250 & 500mg OD, oral route). Blood were drawn 0 time, subsequently samples were drawn at 15, 30, 45 days. Data was analyzed by using SPSS 19.0. Analysis of results showed increase in the Platelet level 19.2%, 65.5%. No significant change seen in the SGPT, Alkaline Phosphatase, WBC, Neutrophil, Lymphocytes, Eosinophils and Monocytes as compared with the controls. It can be concluded that the administration of Papaya seeds powder dose rapidly increase platelet count and may play an important therapeutic role in thrombocytopenia.
本研究的主要目的是评估番木瓜籽对健康家兔血小板计数和肝脏参数的药用作用。在卡拉奇巴凯医科大学药理学系进行实验性和干预性研究。纳入家兔（共18只，不同年龄和性别），随后分为三组（n = 6）。A组（对照组）、B组和C组（分别给予250毫克和500毫克口服剂量的样本）。在0时刻采血，随后在第15、30、45天采集样本。使用SPSS 19.0进行数据分析。结果分析显示血小板水平分别升高了19.2%、65.5%。与对照组相比，谷丙转氨酶、碱性磷酸酶、白细胞、中性粒细胞、淋巴细胞、嗜酸性粒细胞和单核细胞未见显著变化。可以得出结论，给予番木瓜籽粉剂量可迅速增加血小板计数，可能在血小板减少症中发挥重要治疗作用。
