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甲氧苄啶-硫酸多粘菌素B眼膏治疗细菌性结膜炎:与氯霉素眼膏的双盲对照研究

Trimethoprim-polymyxin B sulphate ophthalmic ointment in the treatment of bacterial conjunctivitis: a double-blind study versus chloramphenicol ophthalmic ointment.

作者信息

Behrens-Baumann W, Quentin C D, Gibson J R, Calthrop J G, Harvey S G, Booth K

机构信息

Augenklinik and Poliklinik, Georg-August-Universität, Göttingen, West Germany.

出版信息

Curr Med Res Opin. 1988;11(4):227-31. doi: 10.1185/03007998809114240.

DOI:10.1185/03007998809114240
PMID:2850891
Abstract

Forty-two patients with a clinical diagnosis of bacterial conjunctivitis were enrolled in a randomized, double-blind trial. Patients were treated with either trimethoprim-polymyxin B sulphate or chloramphenicol ophthalmic ointments 4-times a day for 7 days. Analysis of clinical evaluation data showed that both treatments were effective and well tolerated, and that there were no statistically significant differences between them with regard to eradication of organisms or clinical improvement.

摘要

42例临床诊断为细菌性结膜炎的患者被纳入一项随机双盲试验。患者分别接受硫酸甲氧苄啶-多粘菌素B或氯霉素眼膏治疗,每天4次,共7天。临床评估数据分析表明,两种治疗方法均有效且耐受性良好,在根除病原体或临床改善方面两者之间无统计学显著差异。

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Trimethoprim-polymyxin B sulphate ophthalmic ointment in the treatment of bacterial conjunctivitis: a double-blind study versus chloramphenicol ophthalmic ointment.甲氧苄啶-硫酸多粘菌素B眼膏治疗细菌性结膜炎:与氯霉素眼膏的双盲对照研究
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