Meleti Marco, Giovannacci Ilaria, Corradi Domenico, Manfredi Maddalena, Merigo Elisabetta, Bonanini Mauro, Vescovi Paolo
Center of Oral Laser Surgery and Oral Pathology, Dental School. Department of Biomedical, Biotechnological and Translational Sciences, Via Gramsci, 14, 43100 Parma, Italy,
Med Oral Patol Oral Cir Bucal. 2015 Jan 1;20(1):e1-6. doi: 10.4317/medoral.19842.
The aim of this work is to report a review of the literature concerning epidemiology, clinical and radiographic features as well as treatment of odontogenic myxofibroma (MF).
The PubMed database was searched using the following keywords: "odontogenic myxofibroma", "odontogenic fibromyxoma", "myxofibroma of the jaw" and "fibromyxoma of the jaw".
Fifteen articles reporting the experience with 24 patients were identified. Male/female ratio was 1:1.4 and the average age 29.5 years. The most frequent location was the mandible. In 66.7% of the cases the radiographic appearance was a multilocular radiolucency. Swelling was observed in 13 patients (92.86%), varying degrees of pain in 5 (35.71%) and paresthesia in only one patient (7.14%). Six out of 24 patients (26.09%) were treated with radical surgery and 17 out of 24 (73.91%) with a conservative approach. In two out of 21 cases (9.52%) a recurrence was reported.
MF is an extremely rare tumour and no agreement exist on the causes of its development. According to the present review, the choice of treatment should depend on variables such as localization, presence of a primary or of a recurrent lesion, age, general medical conditions and aesthetic needs of the patient.
本研究旨在报告一篇关于牙源性黏液纤维瘤（MF）的流行病学、临床及影像学特征以及治疗的文献综述。
使用以下关键词检索PubMed数据库：“牙源性黏液纤维瘤”、“牙源性纤维黏液瘤”、“颌骨黏液纤维瘤”和“颌骨纤维黏液瘤”。
共确定了15篇报告24例患者经验的文章。男女比例为1:1.4，平均年龄29.5岁。最常见的部位是下颌骨。66.7%的病例影像学表现为多房性透射区。13例患者（92.86%）出现肿胀，5例（35.71%）有不同程度疼痛，仅1例患者（7.14%）出现感觉异常。24例患者中有6例（26.09%）接受了根治性手术，24例中有17例（73.91%）采用了保守治疗方法。21例中有2例（9.52%）报告复发。
MF是一种极其罕见的肿瘤，其发生原因尚无定论。根据本综述，治疗方法的选择应取决于病变部位、是否存在原发或复发病变、年龄、患者的一般健康状况和美学需求等因素。
