Say Jana M, van Vreden Caryn, Reilly David J, Brown Louise J, Rabeau James R, King Nicholas J C
ARC Centre of Excellence for Engineered Quantum Systems, Department of Physics and Astronomy, Macquarie University, Sydney, NSW, 2109, Australia.
Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, NSW, 2109, Australia.
Biophys Rev. 2011 Dec;3(4):171-184. doi: 10.1007/s12551-011-0056-5. Epub 2011 Oct 11.
In recent years, nanodiamonds have emerged from primarily an industrial and mechanical applications base, to potentially underpinning sophisticated new technologies in biomedical and quantum science. Nanodiamonds are relatively inexpensive, biocompatible, easy to surface functionalise and optically stable. This combination of physical properties are ideally suited to biological applications, including intracellular labelling and tracking, extracellular drug delivery and adsorptive detection of bioactive molecules. Here we describe some of the methods and challenges for processing nanodiamond materials, detection schemes and some of the leading applications currently under investigation.
近年来，纳米金刚石已从主要用于工业和机械应用，发展到有可能支撑生物医学和量子科学领域复杂的新技术。纳米金刚石相对便宜、具有生物相容性、易于进行表面功能化且光学性质稳定。这些物理特性的组合非常适合生物应用，包括细胞内标记和追踪、细胞外药物递送以及生物活性分子的吸附检测。在此，我们描述一些处理纳米金刚石材料的方法和挑战、检测方案以及目前正在研究的一些主要应用。
