蛋白质结构研究中酪氨酸侧链基团的紫外可见光谱。第1部分：酪氨酸发色团的基本原理和性质。

UV-Vis spectroscopy of tyrosine side-groups in studies of protein structure. Part 1: basic principles and properties of tyrosine chromophore.

作者信息

Antosiewicz Jan M, Shugar David

机构信息

Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Żwirki i Wigury 93, 02-089, Warsaw, Poland.

Institute of Biochemistry & Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106, Warsaw, Poland.

出版信息

Biophys Rev. 2016 Jun;8(2):151-161. doi: 10.1007/s12551-016-0198-6. Epub 2016 May 4.

Spectroscopic properties of tyrosine residues may be employed in structural studies of proteins. Here we discuss several different types of UV-Vis spectroscopy, like normal, difference and second-derivative UV absorption spectroscopy, fluorescence spectroscopy, linear and circular dichroism spectroscopy, and Raman spectroscopy, and corresponding optical properties of the tyrosine chromophore, phenol, which are used to study protein structure.