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丘疹结节性二期梅毒在一名HIV阳性的跨性别女性中表现为多个不同的皮肤病变。

Papulonodular Secondary Syphilis Presenting as Multiple Distinct Cutaneous Lesions in an HIV-Positive Transgender Woman.

作者信息

Navrazhina Kristina, Cressey Brienne D, Minkis Kira

机构信息

Department of Dermatology, Weill Cornell Medical College, New York, New York, USA.

出版信息

Case Rep Dermatol. 2017 Mar 29;9(1):90-94. doi: 10.1159/000456065. eCollection 2017 Jan-Apr.

DOI:10.1159/000456065
PMID:28512403
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5422738/
Abstract

We present the first reported case of papulonodular secondary syphilis in an HIV-positive transgender female. Syphilis is classified into primary, secondary, latent, and tertiary stages, with secondary syphilis having notably diverse cutaneous manifestations. Our patient presented with diverse lesions throughout her body, all pathologically consistent with papulonodular secondary syphilis. Proper identification of the multiple presentations of syphilis is crucial to early diagnosis and treatment. This report seeks to broaden the scope of dermatological manifestations that arise secondary to papulonodular syphilis in HIV-positive patients.

摘要

我们报告了首例人类免疫缺陷病毒(HIV)阳性的跨性别女性患丘疹结节性二期梅毒的病例。梅毒分为一期、二期、潜伏期和三期,二期梅毒有明显多样的皮肤表现。我们的患者全身出现多种损害,所有病理表现均符合丘疹结节性二期梅毒。正确识别梅毒的多种表现形式对于早期诊断和治疗至关重要。本报告旨在扩大HIV阳性患者中丘疹结节性梅毒继发的皮肤表现范围。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e771/5422738/95ef9ac0797d/cde-0009-0090-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e771/5422738/c1de91096c79/cde-0009-0090-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e771/5422738/95ef9ac0797d/cde-0009-0090-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e771/5422738/c1de91096c79/cde-0009-0090-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e771/5422738/95ef9ac0797d/cde-0009-0090-g02.jpg

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本文引用的文献

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Papulonodular secondary syphilis: a rare clinic presentation confirmed by serologic and histologic exams.丘疹结节性二期梅毒:一种经血清学和组织学检查确诊的罕见临床表型。
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2
Sexually Transmitted Diseases: Summary of 2015 CDC Treatment Guidelines.性传播疾病:2015年美国疾病控制与预防中心治疗指南摘要
J Miss State Med Assoc. 2015 Dec;56(12):372-5.
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One dose versus three weekly doses of benzathine penicillin G for patients co-infected with HIV and early syphilis: a multicenter, prospective observational study.
苄星青霉素G单剂量与三周一次共三次剂量用于HIV合并早期梅毒患者的疗效比较:一项多中心前瞻性观察研究
PLoS One. 2014 Oct 6;9(10):e109667. doi: 10.1371/journal.pone.0109667. eCollection 2014.
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Nodular secondary syphilis with associated granulomatous inflammation: case report and literature review.结节性二期梅毒伴肉芽肿性炎症:病例报告及文献复习
J Cutan Pathol. 2014 Apr;41(4):370-9. doi: 10.1111/cup.12293. Epub 2014 Feb 13.
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Papulonodular secondary syphilis in a 52-year-old non-HIV heterosexual patient.一名52岁非HIV感染的异性恋患者的丘疹结节性二期梅毒。
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Cutaneous manifestations of syphilis : recognition and management.梅毒的皮肤表现:识别与管理
Am J Clin Dermatol. 2006;7(5):291-304. doi: 10.2165/00128071-200607050-00003.
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