后皮质萎缩所致同向性偏盲
Homonymous Hemianopsia Due to Posterior Cortical Atrophy.
作者信息
Pellegrini Francesco, Lee Andrew G, Zucchetta Pietro
机构信息
Neuro-Ophthalmology Service, Department of Ophthalmology, Conegliano Hospital, Conegliano (TV), Italy.
Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas, USA.
出版信息
Neuroophthalmology. 2017 Feb 15;41(3):154-158. doi: 10.1080/01658107.2016.1278556. eCollection 2017 Jun.
Abstract
A 63-year-old woman presented to her ophthalmologist complaining of reading difficulties for two years. Ophthalmological examination revealed a homonymous hemianopsia. Brain magnetic resonance imaging (MRI) scan was interpreted as normal, but positron emission tomography (PET) showed areas of posterior brain hypometabolism. This case highlights the high diagnostic suspicion that ophthalmologists should have regarding posterior cortical atrophy (including the visual variant of Alzheimer disease) in patients complaining of reading difficulties in the setting of a normal ophthalmic examination.
摘要
一名63岁女性因阅读困难两年就诊于眼科医生。眼科检查发现同向偏盲。脑部磁共振成像（MRI）扫描结果被判定为正常，但正电子发射断层扫描（PET）显示后脑存在代谢减低区域。该病例突出表明，对于眼科检查正常但主诉阅读困难的患者，眼科医生应高度怀疑其患有后皮质萎缩（包括阿尔茨海默病的视觉变异型）。
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2
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