Park YoonAh, Park Kun-Woo, Lee Chan-Nyeong
Department of Neurology, Korea University Medical Center, Seoul, Korea.
Dement Neurocogn Disord. 2017 Dec;16(4):128-131. doi: 10.12779/dnd.2017.16.4.128. Epub 2017 Dec 31.
Alzheimer's disease is a chronic neurodegenerative condition, mostly affecting the medial temporal lobe and associated neocortical structures. In this report, we present a rare clinical manifestation of this disease.
A 61-year-old female with word finding difficulty and memory disturbances was diagnosed with Alzheimer's disease. Two years later, she complained of right homonymous hemianopia without optic ataxia, ocular apraxia, and simultagnosia. No findings other than parenchymal disease were apparent in magnetic resonance imaging and laboratory tests.
In this case, in a patient initially diagnosed with Alzheimer's dementia with progressive disease, we found only homonymous hemianopia, without signs of Balint's syndrome or Gerstmann's syndrome. After careful investigation showing that Alzheimer's dementia with visual symptom was not associated with parenchymal disease, we concluded a case of atypical variant of Alzheimer's disease.
阿尔茨海默病是一种慢性神经退行性疾病,主要影响内侧颞叶及相关的新皮质结构。在本报告中,我们展示了该疾病一种罕见的临床表现。
一名61岁女性,存在找词困难和记忆障碍,被诊断为阿尔茨海默病。两年后,她主诉右侧同向性偏盲,无视觉共济失调、眼球失用和同时失认。磁共振成像和实验室检查除实质性疾病外无其他异常发现。
在该病例中,一名最初被诊断为进行性阿尔茨海默痴呆的患者,我们仅发现同向性偏盲,无巴林特综合征或格斯特曼综合征的体征。经过仔细检查表明,伴有视觉症状的阿尔茨海默痴呆与实质性疾病无关,我们诊断为阿尔茨海默病的非典型变异型病例。