正常人类角膜及疱疹性角膜炎病例角膜中MHC I类和II类抗原的表达
MHC class I and class II antigen expression in normal human corneas and in corneas from cases of herpetic keratitis.
作者信息
McBride B W, McGill J I, Smith J L
机构信息
University Department of Medical Microbiology, Southampton General Hospital.
出版信息
Immunology. 1988 Dec;65(4):583-7.
Abstract
The expression of HLA class I and class II antigens in corneas from normal donors and patients with quiescent herpetic keratitis was investigated using specific monoclonal antibodies. Keratocytes from diseased corneas showed aberrant expression of HLA class I and class II (DR, DP and DQ) antigens. The expression of HLA antigens in these corneas was not associated with immune cell infiltrates or viral antigens.
摘要
使用特异性单克隆抗体研究了正常供体角膜和静止性疱疹性角膜炎患者角膜中HLA I类和II类抗原的表达。患病角膜的角膜细胞显示出HLA I类和II类（DR、DP和DQ）抗原的异常表达。这些角膜中HLA抗原的表达与免疫细胞浸润或病毒抗原无关。
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