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本文引用的文献

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Viral infection in community-acquired pneumonia: a systematic review and meta-analysis.社区获得性肺炎中的病毒感染：一项系统评价和荟萃分析。
Eur Respir Rev. 2016 Jun;25(140):178-88. doi: 10.1183/16000617.0076-2015.
2
Impact of Multiplex Polymerase Chain Reaction Testing for Respiratory Pathogens on Healthcare Resource Utilization for Pediatric Inpatients.多重聚合酶链反应检测呼吸道病原体对儿科住院患者医疗资源利用的影响
J Pediatr. 2016 Jun;173:196-201.e2. doi: 10.1016/j.jpeds.2016.02.050. Epub 2016 Mar 30.
3
Comprehensive Molecular Testing for Respiratory Pathogens in Community-Acquired Pneumonia.社区获得性肺炎中呼吸道病原体的综合分子检测
Clin Infect Dis. 2016 Apr 1;62(7):817-823. doi: 10.1093/cid/civ1214. Epub 2016 Jan 7.
4
Rapid Diagnosis of Infection in the Critically Ill, a Multicenter Study of Molecular Detection in Bloodstream Infections, Pneumonia, and Sterile Site Infections.危重症患者感染的快速诊断：一项关于血流感染、肺炎及无菌部位感染分子检测的多中心研究
Crit Care Med. 2015 Nov;43(11):2283-91. doi: 10.1097/CCM.0000000000001249.
5
Clinical practice. Community-acquired pneumonia.临床实践。社区获得性肺炎。
N Engl J Med. 2014 Feb 6;370(6):543-51. doi: 10.1056/NEJMcp1214869.
6
Acute respiratory distress syndrome secondary to human metapneumovirus infection in a young healthy adult.一名年轻健康成年人继发人偏肺病毒感染后的急性呼吸窘迫综合征
Intensive Care Med. 2013 Mar;39(3):533-4. doi: 10.1007/s00134-012-2777-8. Epub 2013 Jan 4.
7
[Study of hospitalizations for pneumococcal pneumoniae in Centre region, 2004-2008].[2004 - 2008年中部地区肺炎球菌肺炎住院情况研究]
Rev Epidemiol Sante Publique. 2012 Feb;60(1):1-8. doi: 10.1016/j.respe.2011.07.005. Epub 2012 Jan 14.
8
High burden of non-influenza viruses in influenza-like illness in the early weeks of H1N1v epidemic in France.高负担的非流感病毒在法国 H1N1v 流感疫情早期的流感样疾病中。
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多重PCR检测呼吸道病原体对医疗决策过程的影响。

Impact on the medical decision-making process of multiplex PCR assay for respiratory pathogens.

作者信息

Guillon A, Aymeric S, Gaudy-Graffin C, Sonke J, Deblonde M P, Capsec J, Diot P, Garot D, Goudeau A, Grammatico-Guillon L

机构信息

Service de Réanimation Polyvalente,CHRU de Tours,Université François Rabelais,CEPR, U1100, Tours,France.

Laboratoire de Santé Publique,CHRU de Tours,Université François Rabelais, EE Education Ethique Santé,Tours,France.

出版信息

Epidemiol Infect. 2017 Oct;145(13):2766-2769. doi: 10.1017/S0950268817001029. Epub 2017 May 18.

DOI:10.1017/S0950268817001029
PMID:28516828
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9148783/
Abstract

The objective of this study was to determine how clinicians make use of the modern multiplex PCR assays (MPAs) to manage patients hospitalized for community-acquired pneumonia (CAP). We studied the use of MPAs in 1648 patients hospitalized for CAP over a 3-year period at the moment of the setup of the new PCR assay. We observed that the use of MPAs for the identification of multiple respiratory pathogens marks a radical change in the investigation of CAP etiology. Surprisingly, the contribution of MPAs to the medical decision-making process varies drastically according to the units of care.

摘要

本研究的目的是确定临床医生如何利用现代多重聚合酶链反应检测法（MPAs）来管理因社区获得性肺炎（CAP）住院的患者。在新的聚合酶链反应检测法建立之时，我们对1648例因CAP住院的患者进行了为期3年的MPAs使用情况研究。我们观察到，使用MPAs来鉴定多种呼吸道病原体标志着CAP病因调查的一个根本性变化。令人惊讶的是，MPAs对医疗决策过程的贡献因护理单元而异。