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SU-E-T-95:拟人化脊柱体模的三维剂量学研究。

SU-E-T-95: Investigation of 3D Dosimetry for an Anthropomorphic Spine Phantom.

作者信息

Grant R, Ibbott G, Yang J, Adamovics J, Followill D

机构信息

MD Anderson Cancer Center, Houston, TX.

Graduate School of Biomedical Sciences, Houston, TX.

出版信息

Med Phys. 2012 Jun;39(6Part11):3724. doi: 10.1118/1.4735152.

Abstract

PURPOSE

To evaluate 3D dosimetry for a spinal cord treatment plan delivery using the Radiological Physics Center's (RPC) anthropomorphic spine phantom.

METHODS

The RPC's spine phantom currently uses radiochromic film and thermoluminescent dosimeters (TLD) to evaluate spinal metastases treatments. A second dosimetry insert for the phantom was created to hold a PRESAGE® 3D dosimeter which matched the location of the TLD and film in the original insert. The phantom was CT imaged with each insert and an IMRT treatment plan was developed. The IMRT plan was delivered to the phantom twice; once with each insert. The film and PRESAGE® were scanned on a CCD microdensitometer and optical-CT system, reconstructed to a 2 mm slice width, respectively. The measured dose distributions were compared to the treatment plan calculated dose distribution using RPC in-house developed software or the Computational Environment for Radiotherapy Research (CERR). Film and PRESAGE® dose profiles were taken across several planes and compared for agreement. The distance to agreement (DTA) between the measured data and treatment plan, within the high dose gradient region, was quantified.

RESULTS

The PRESAGE® and plan dose profiles agreed to within 2and 1 mm in the AP and SI directions, respectively. The film and plan also agreed to within 2 mm across all profiles.

CONCLUSIONS

The PRESAGE® 3D dosimeter, based on these preliminary data, shows potential as a dosimeter for the RPC's phantom irradiation studies. Future work will add markers to the PRESAGE® insert to allow for a reproducible registration in CERR and a an optical-CT system, reconstructed to a 2 mm slice width dose calibration protocol will be created. CA 100835.

摘要

目的

使用放射物理中心(RPC)的人体脊柱模型评估脊髓治疗计划传输的三维剂量测定法。

方法

RPC的脊柱模型目前使用放射变色胶片和热释光剂量计(TLD)来评估脊柱转移瘤的治疗。为该模型制作了第二个剂量测定插入件,用于放置一个与原始插入件中TLD和胶片位置匹配的PRESAGE®三维剂量计。对带有每个插入件的模型进行CT成像,并制定调强放疗(IMRT)治疗计划。将IMRT计划对模型进行两次传输;每次使用一个插入件。分别在电荷耦合器件(CCD)微密度计和光学CT系统上扫描胶片和PRESAGE®,重建为2毫米的切片宽度。使用RPC内部开发的软件或放射治疗研究计算环境(CERR),将测量的剂量分布与治疗计划计算的剂量分布进行比较。在几个平面上获取胶片和PRESAGE®的剂量分布图,并比较其一致性。对高剂量梯度区域内测量数据与治疗计划之间的一致距离(DTA)进行量化。

结果

PRESAGE®与计划剂量分布图在前后(AP)方向和头脚(SI)方向上分别在2毫米和1毫米内一致。胶片与计划在所有分布图上也在2毫米内一致。

结论

基于这些初步数据,PRESAGE®三维剂量计显示出作为RPC模型照射研究剂量计的潜力。未来的工作将在PRESAGE®插入件上添加标记,以便在CERR中进行可重复的配准,并将创建一个重建为2毫米切片宽度的剂量校准方案。加利福尼亚州100835。

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