• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

在瑞士一名肾移植受者中，从慢性戊型肝炎病毒感染中分离出一种新型戊型肝炎病毒3型毒株的鉴定。

Identification of a Novel Hepatitis E Virus Genotype 3 Strain Isolated from a Chronic Hepatitis E Virus Infection in a Kidney Transplant Recipient in Switzerland.

作者信息

Wang Bo, Harms Dominik, Hofmann Jörg, Ciardo Diana, Kneubühl Agnes, Bock C-Thomas

机构信息

Department of Infectious Diseases, Robert Koch Institute, Berlin, Germany.

Institute of Medical Virology, Charité University Medicine, Berlin, Germany.

出版信息

Genome Announc. 2017 May 18;5(20):e00345-17. doi: 10.1128/genomeA.00345-17.

DOI:10.1128/genomeA.00345-17
PMID:28522709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5442380/
Abstract

Hepatitis E virus genotype 3 (HEV-3) is the causal pathogen of chronic hepatitis E. We report here the full-length genome sequence of an HEV-3 strain, isolated from a kidney transplant recipient in Switzerland (SW/16-0282). This HEV-3 strain showed less than 88% homology compared to known strains, suggesting a new HEV-3 strain.

摘要

戊型肝炎病毒3型（HEV-3）是慢性戊型肝炎的致病病原体。我们在此报告从瑞士一名肾移植受者（SW/16-0282）分离出的一株HEV-3毒株的全长基因组序列。与已知毒株相比，该HEV-3毒株的同源性低于88%，提示这是一种新的HEV-3毒株。

相似文献

1
Identification of a Novel Hepatitis E Virus Genotype 3 Strain Isolated from a Chronic Hepatitis E Virus Infection in a Kidney Transplant Recipient in Switzerland.在瑞士一名肾移植受者中，从慢性戊型肝炎病毒感染中分离出一种新型戊型肝炎病毒3型毒株的鉴定。
Genome Announc. 2017 May 18;5(20):e00345-17. doi: 10.1128/genomeA.00345-17.
2
Comprehensive Molecular Approach for Characterization of Hepatitis E Virus Genotype 3 Variants.全面的分子方法用于鉴定戊型肝炎病毒 3 型变异株。
J Clin Microbiol. 2018 Apr 25;56(5). doi: 10.1128/JCM.01686-17. Print 2018 May.
3
Identification of a putative novel genotype 3/rabbit hepatitis E virus (HEV) recombinant.鉴定一种新型的基因型 3/兔乙型肝炎病毒（HEV）重组病毒。
PLoS One. 2018 Sep 11;13(9):e0203618. doi: 10.1371/journal.pone.0203618. eCollection 2018.
4
Full-length genome of a novel genotype 3 hepatitis E virus strain obtained from domestic pigs in Japan.从日本家猪中分离得到的新型3型戊型肝炎病毒株的全长基因组
Virus Res. 2017 Aug 15;240:147-153. doi: 10.1016/j.virusres.2017.08.003. Epub 2017 Aug 16.
5
Full-length genomic sequences of new subtype 1g hepatitis E virus strains obtained from four patients with imported or autochthonous acute hepatitis E in Japan.从日本四名输入性或本土性急性戊型肝炎患者中获得的新 1g 型戊型肝炎病毒全长基因组序列。
Infect Genet Evol. 2017 Nov;55:343-349. doi: 10.1016/j.meegid.2017.10.007. Epub 2017 Oct 5.
6
Distinct changing profiles of hepatitis A and E virus infection among patients with acute hepatitis in Mongolia: The first report of the full genome sequence of a novel genotype 1 hepatitis E virus strain.蒙古国急性肝炎患者中甲型和戊型肝炎病毒感染的不同变化特征：新型基因型 1 戊型肝炎病毒株全基因组序列的首次报告。
J Med Virol. 2018 Jan;90(1):84-92. doi: 10.1002/jmv.24907. Epub 2017 Oct 6.
7
Analysing complete genome sequence of swine hepatitis E virus (HEV), strain CHN-XJ-SW13 isolated from Xinjiang, China: putative host range, and disease severity determinants in HEV.分析从中国新疆分离的猪戊型肝炎病毒（HEV）株 CHN-XJ-SW13 的全基因组序列：HEV 的可能宿主范围和疾病严重程度决定因素。
Infect Genet Evol. 2011 Apr;11(3):618-23. doi: 10.1016/j.meegid.2011.01.018. Epub 2011 Feb 1.
8
Genome sequence of a hepatitis e virus of genotype 3e from a chronically infected kidney transplant recipient.一名慢性感染的肾移植受者体内3e基因型戊型肝炎病毒的基因组序列。
Genome Announc. 2014 Jan 30;2(1):e01156-13. doi: 10.1128/genomeA.01156-13.
9
First report and molecular characterization of hepatitis E virus infection in renal transplant recipients in Brazil.巴西首例肾移植受者戊型肝炎病毒感染的报告及分子特征。
J Med Virol. 2013 Apr;85(4):615-9. doi: 10.1002/jmv.23494. Epub 2013 Feb 4.
10
Full genome analysis of swine genotype 3 hepatitis E virus isolated from eastern China.对来自中国东部的猪3型戊型肝炎病毒进行全基因组分析。
J Zhejiang Univ Sci B. 2017 Jun;18(6):549-554. doi: 10.1631/jzus.B1600419.

引用本文的文献

1
Identification of novel rodent and shrew orthohepeviruses sheds light on hepatitis E virus evolution.新型啮齿动物和鼩鼱正戊型肝炎病毒的鉴定为戊型肝炎病毒的进化提供了线索。
Zool Res. 2025 Jan 18;46(1):103-121. doi: 10.24272/j.issn.2095-8137.2024.298.
2
Phosphorylation of Ser711 residue in the hypervariable region of zoonotic genotype 3 hepatitis E virus is important for virus replication.在人畜共患基因型 3 型肝炎病毒的高变区中丝氨酸 711 残基的磷酸化对病毒复制很重要。
mBio. 2024 Nov 13;15(11):e0263524. doi: 10.1128/mbio.02635-24. Epub 2024 Oct 8.
3
Ribavirin Treatment Failure-Associated Mutation, Y1320H, in the RNA-Dependent RNA Polymerase of Genotype 3 Hepatitis E Virus (HEV) Enhances Virus Replication in a Rabbit HEV Infection Model.Y1320H 核糖核酸依赖的核糖核酸聚合酶基因变异与利巴韦林治疗失败相关，可增强基因型 3 型戊型肝炎病毒（HEV）在兔 HEV 感染模型中的复制。
mBio. 2023 Apr 25;14(2):e0337222. doi: 10.1128/mbio.03372-22. Epub 2023 Feb 21.
4
Serological, Virological Investigation and Hepatic Injury Evaluation for Hepatitis E Virus in Hunting Dogs.猎犬戊型肝炎病毒的血清学、病毒学调查及肝损伤评估
Pathogens. 2022 Sep 29;11(10):1123. doi: 10.3390/pathogens11101123.
5
Hepatitis E virus infects brain microvascular endothelial cells, crosses the blood-brain barrier, and invades the central nervous system.戊型肝炎病毒感染脑微血管内皮细胞，穿过血脑屏障，侵犯中枢神经系统。
Proc Natl Acad Sci U S A. 2022 Jun 14;119(24):e2201862119. doi: 10.1073/pnas.2201862119. Epub 2022 Jun 7.
6
Genetic Diversity of Hepatitis E Virus Type 3 in Switzerland-From Stable to Table.瑞士戊型肝炎病毒3型的遗传多样性——从稳定到餐桌。
Animals (Basel). 2021 Nov 7;11(11):3177. doi: 10.3390/ani11113177.
7
Screening of Swiss Pig Herds for Hepatitis E Virus: A Pilot Study.瑞士猪群戊型肝炎病毒筛查：一项试点研究。
Animals (Basel). 2021 Oct 25;11(11):3050. doi: 10.3390/ani11113050.
8
Detection and genomic characterization of hepatitis E virus genotype 3 from pigs in Ghana, Africa.非洲加纳猪群中戊型肝炎病毒3型的检测及基因组特征分析
One Health Outlook. 2020 Jul 20;2:10. doi: 10.1186/s42522-020-00018-3. eCollection 2020.
9
Viral Hepatitis E and Chronicity: A Growing Public Health Concern.戊型病毒性肝炎与慢性化：日益受到关注的公共卫生问题
Front Microbiol. 2020 Sep 29;11:577339. doi: 10.3389/fmicb.2020.577339. eCollection 2020.
10
Swine hepatitis E virus: Cross-species infection, pork safety and chronic infection.猪戊型肝炎病毒：跨种感染、猪肉安全和慢性感染。
Virus Res. 2020 Jul 15;284:197985. doi: 10.1016/j.virusres.2020.197985. Epub 2020 Apr 23.

本文引用的文献

1
Detection and genome characterization of four novel bat hepadnaviruses and a hepevirus in China.中国四种新型蝙蝠嗜肝DNA病毒和一种戊型肝炎病毒的检测及基因组特征分析
Virol J. 2017 Feb 22;14(1):40. doi: 10.1186/s12985-017-0706-8.
2
Hepatitis E Virus Mutations: Functional and Clinical Relevance.戊型肝炎病毒突变：功能及临床相关性
EBioMedicine. 2016 Sep;11:31-42. doi: 10.1016/j.ebiom.2016.07.039. Epub 2016 Aug 6.
3
Chronic Infection With Camelid Hepatitis E Virus in a Liver Transplant Recipient Who Regularly Consumes Camel Meat and Milk.肝移植受者长期食用骆驼肉和奶而慢性感染骆驼肝炎 E 病毒。
Gastroenterology. 2016 Feb;150(2):355-7.e3. doi: 10.1053/j.gastro.2015.10.048. Epub 2015 Nov 6.
4
The impact of hepatitis E in the liver transplant setting.戊型肝炎在肝移植中的影响。
J Hepatol. 2014 Dec;61(6):1418-29. doi: 10.1016/j.jhep.2014.08.047. Epub 2014 Sep 6.
5
Pathogenesis and treatment of hepatitis e virus infection.戊型肝炎病毒感染的发病机制与治疗。
Gastroenterology. 2012 May;142(6):1388-1397.e1. doi: 10.1053/j.gastro.2012.02.014.
6
Hepatitis E Virus seroprevalence and chronic infections in patients with HIV, Switzerland.瑞士 HIV 感染者中戊型肝炎病毒血清流行率和慢性感染情况。
Emerg Infect Dis. 2011 Jun;17(6):1074-8. doi: 10.3201/eid/1706.101067.
7
Hepatitis E virus seroprevalence among blood donors in southwest Switzerland.瑞士西南部献血者中戊型肝炎病毒血清流行率。
PLoS One. 2011;6(6):e21150. doi: 10.1371/journal.pone.0021150. Epub 2011 Jun 20.
8
Hepatitis E in high-income countries.在高收入国家的戊型肝炎。
Curr Opin Infect Dis. 2010 Oct;23(5):521-7. doi: 10.1097/QCO.0b013e32833de683.
9
Hepatitis E virus: animal reservoirs and zoonotic risk.戊型肝炎病毒：动物宿主与人畜共患病风险。
Vet Microbiol. 2010 Jan 27;140(3-4):256-65. doi: 10.1016/j.vetmic.2009.03.017. Epub 2009 Mar 20.
10
Hepatitis E virus and chronic hepatitis in organ-transplant recipients.戊型肝炎病毒与器官移植受者的慢性肝炎
N Engl J Med. 2008 Feb 21;358(8):811-7. doi: 10.1056/NEJMoa0706992.