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新型生物标志物与生物标志物在炎症性肠病中的未来潜力

Novel Biomarkers and the Future Potential of Biomarkers in Inflammatory Bowel Disease.

作者信息

Duvoisin Gilles, Lopez Robert N, Day Andrew S, Lemberg Daniel A, Gearry Richard B, Leach Steven T

机构信息

Department of Paediatrics, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Department of Gastroenterology, Sydney Children's Hospital Randwick, Sydney, Australia.

出版信息

Mediators Inflamm. 2017;2017:1936315. doi: 10.1155/2017/1936315. Epub 2017 Apr 16.

Abstract

There is increasing importance placed upon noninvasive assessment of gut inflammation. These tools are likely to be the key in differentiating intestinal inflammatory disease from functional disorders and in monitoring the response to intervention in individuals with known inflammatory conditions. Although various noninvasive markers are currently available, they have limitations and do not provide ideal utility. This review focuses on emerging markers of gut inflammation, highlighting the potential of specific markers.

摘要

肠道炎症的非侵入性评估正变得越来越重要。这些工具可能是区分肠道炎症性疾病与功能性疾病以及监测已知炎症状态个体对干预反应的关键。尽管目前有多种非侵入性标志物可用,但它们存在局限性,无法提供理想的效用。本综述重点关注肠道炎症的新兴标志物,突出特定标志物的潜力。

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