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一名柯萨奇病毒感染患者的金氏金杆菌败血症

[Kingella kingae septicemia in a patient with coxsackievirus infection].

作者信息

Huard A, Van Fraechem G, Gerain J, Van Hove M, Cosyns B

机构信息

Hôpital de Braine-l'Alleud, Waterloo Service de Médecine Interne et Endocrinologie, Rue Wayez 35, Braine-l'Alleud, Belgium.

Service de Maladies Infectieuses et Médecine Tropicale, Belgium; Gerain, J., Clinique Du Parc Léopold, Service de Maladies Infectieuses, Belgium.

出版信息

Rev Med Brux. 2016;37(5):419-422.

Abstract

Kingella kingae is a gram-negative cocci present in the oral flora ; this organism is difficult to isolate by conventional culture techniques ; it can be detected after longer incubation period (more than 6 days) in blood culture. It is responsible of various infectious diseases, especially in children below 3 years-old where it is a cause of arthritis and osteomyeli tis. It is included in HACEK organisms responsible of 2 to 3 % of all cases of native endocarditis. The case report is the case of a young women with Kingella kingae septicemia in a context of oral lesions from Coxsackie virus infection ; treatment by ciprofloxacine permit a complete resolution of symptoms. Differential diagnosis is made about conditions with oral lesions. This article is an occasion to review literature about this unusual organism and clinical presentation. Improvements in laboratory method will in the future increase incidence and prevalence of infections caused by Kingella kingae.

摘要

金氏金杆菌是一种存在于口腔菌群中的革兰氏阴性球菌;这种微生物很难通过传统培养技术分离出来;在血培养中经过较长潜伏期(超过6天)后才能检测到。它会引发各种传染病,尤其是在3岁以下儿童中,它是关节炎和骨髓炎的病因。它属于HACEK菌群,在所有原发性心内膜炎病例中占2%至3%。该病例报告讲述的是一名年轻女性,在感染柯萨奇病毒导致口腔病变的情况下发生了金氏金杆菌败血症;环丙沙星治疗使症状完全缓解。对伴有口腔病变的病症进行了鉴别诊断。本文提供了一个回顾关于这种不寻常微生物及其临床表现的文献的机会。实验室方法的改进未来将增加金氏金杆菌引起的感染的发病率和患病率。

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