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联邦监管20年后加拿大阿片类激动剂疗法的现状

The State of Opioid Agonist Therapy in Canada 20 Years after Federal Oversight.

作者信息

Eibl Joseph K, Morin Kristen, Leinonen Esa, Marsh David C

机构信息

1 Northern Ontario School of Medicine, Sudbury, Ontario.

2 Laurentian University, Sudbury, Ontario.

出版信息

Can J Psychiatry. 2017 Jul;62(7):444-450. doi: 10.1177/0706743717711167. Epub 2017 May 19.

DOI:10.1177/0706743717711167
PMID:28525291
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5528991/
Abstract

Opioid agonist therapy was introduced in Canada in 1959 with the use of methadone for the treatment of opioid dependence. The regulation of methadone was the responsibility of Health Canada until 1995, when oversight was transferred to the provincial health systems. During the more than 20 years since the federal health authority transferred oversight of methadone to the provincial level, methadone programming has evolved differently in every province. The landscape of opioid dependence treatment is varied across the country, with generally increasing treatment capacity in all provinces and dramatic increases in some. Each province has an independent methadone program with differing policies, contingency management strategies, laboratory monitoring policies, and delivery methods. Treatment options have increased, with buprenorphine- and heroin-assisted treatment becoming available to limited degrees. Despite this, access remains a challenge in many parts of the country (particularly rural and remote areas) because the demand for treatment has increased even more rapidly than the capacity. Although treatment access remains a priority in many jurisdictions, there is also a need to attend to treatment quality as treatment access expands, including integration with addiction counselling, primary care, and mental health care. As well, coordinated monitoring and reporting of treatment need, quality, and delivery are required; implementing a national policy to promote planning would have tremendous value.

摘要

1959年,阿片类激动剂疗法在加拿大引入,当时使用美沙酮治疗阿片类药物依赖。直到1995年,美沙酮的监管一直由加拿大卫生部负责,之后监管权移交给了省级卫生系统。自联邦卫生当局将美沙酮监管权移交给省级以来的20多年里,每个省份的美沙酮项目发展情况各不相同。全国阿片类药物依赖治疗的情况各不相同,所有省份的治疗能力总体上都在增加,有些省份增加显著。每个省份都有独立的美沙酮项目,其政策、应急管理策略、实验室监测政策和给药方式各不相同。治疗选择有所增加,丁丙诺啡和海洛因辅助治疗在一定程度上也已可用。尽管如此,在该国许多地区(特别是农村和偏远地区),获得治疗仍然是一项挑战,因为治疗需求的增长速度甚至超过了治疗能力的增长速度。尽管在许多司法管辖区,获得治疗仍然是优先事项,但随着治疗机会的扩大,也需要关注治疗质量,包括与成瘾咨询、初级保健和精神卫生保健的整合。此外,还需要对治疗需求、质量和提供情况进行协调监测和报告;实施一项促进规划的国家政策将具有巨大价值。

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Geographic Variations in Prescription Opioid Dispensations and Deaths Among Women and Men in British Columbia, Canada.加拿大不列颠哥伦比亚省男女处方阿片类药物配药及死亡情况的地理差异
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Trends and sex differences in prescription opioid deaths in British Columbia, Canada.加拿大不列颠哥伦比亚省处方阿片类药物死亡的趋势及性别差异。
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Impact of legislation and a prescription monitoring program on the prevalence of potentially inappropriate prescriptions for monitored drugs in Ontario: a time series analysis.立法和处方监测计划对安大略省受监测药物潜在不适当处方流行率的影响:一项时间序列分析
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