Katheria Anup C, Brown Melissa K, Faksh Arij, Hassen Kasim O, Rich Wade, Lazarus Danielle, Steen Jane, Daneshmand Shahram Sean, Finer Neil N
Department of Perinatology, Neonatal Research Institute at Sharp Mary Birch Hospital for Women and Newborns, San Diego, CA.
Department of Perinatology, Neonatal Research Institute at Sharp Mary Birch Hospital for Women and Newborns, San Diego, CA.
J Pediatr. 2017 Aug;187:313-317.e1. doi: 10.1016/j.jpeds.2017.04.033. Epub 2017 May 16.
Infants may benefit if resuscitation could be provided with an intact umbilical cord. Infants identified at risk for resuscitation were randomized to 1- or 5-minute cord clamping. The 5-minute group had greater cerebral oxygenation and blood pressure. Studies are needed to determine whether this translates into improved outcomes.
ClinicalTrials.gov: NCT02827409.
如果能在脐带完整的情况下进行复苏，婴儿可能会受益。被确定有复苏风险的婴儿被随机分为脐带结扎1分钟或5分钟组。5分钟组的脑氧合和血压更高。需要开展研究来确定这是否能转化为更好的结局。
ClinicalTrials.gov：NCT02827409。
