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足月出生有复苏风险新生儿的延迟脐带结扎:一项可行性随机临床试验。

Delayed Cord Clamping in Newborns Born at Term at Risk for Resuscitation: A Feasibility Randomized Clinical Trial.

作者信息

Katheria Anup C, Brown Melissa K, Faksh Arij, Hassen Kasim O, Rich Wade, Lazarus Danielle, Steen Jane, Daneshmand Shahram Sean, Finer Neil N

机构信息

Department of Perinatology, Neonatal Research Institute at Sharp Mary Birch Hospital for Women and Newborns, San Diego, CA.

Department of Perinatology, Neonatal Research Institute at Sharp Mary Birch Hospital for Women and Newborns, San Diego, CA.

出版信息

J Pediatr. 2017 Aug;187:313-317.e1. doi: 10.1016/j.jpeds.2017.04.033. Epub 2017 May 16.

Abstract

UNLABELLED

Infants may benefit if resuscitation could be provided with an intact umbilical cord. Infants identified at risk for resuscitation were randomized to 1- or 5-minute cord clamping. The 5-minute group had greater cerebral oxygenation and blood pressure. Studies are needed to determine whether this translates into improved outcomes.

TRIAL REGISTRATION

ClinicalTrials.gov: NCT02827409.

摘要

未标注

如果能在脐带完整的情况下进行复苏,婴儿可能会受益。被确定有复苏风险的婴儿被随机分为脐带结扎1分钟或5分钟组。5分钟组的脑氧合和血压更高。需要开展研究来确定这是否能转化为更好的结局。

试验注册

ClinicalTrials.gov:NCT02827409。

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