Bradley/Hasbro Children's Research Center, Providence, RI; Alpert Medical School, Brown University, Providence, RI,; Hasbro Children's Hospital/Rhode Island Hospital, Providence, RI.
Bradley/Hasbro Children's Research Center, Providence, RI; Alpert Medical School, Brown University, Providence, RI,; Hasbro Children's Hospital/Rhode Island Hospital, Providence, RI.
Sleep Health. 2017 Jun;3(3):148-156. doi: 10.1016/j.sleh.2017.03.008. Epub 2017 Apr 11.
Examine (1) the extent to which changes in objectively measured asthma-related lung function (forced expiratory volume in 1 second) within a sleep period are associated with sleep quality and sleep duration during that sleep period in a group of urban children with persistent asthma, (2) associations between morning and evening asthma-related lung function and sleep quality and duration on the adjacent night, and (3) whether these associations differ by ethnic group.
Cross-sectional, multimethod approach. Children completed a clinic assessment of asthma and allergy status and used home-based objective measurements of asthma-related lung function and sleep.
Children and their caregivers participated in a clinic assessment at an asthma and allergy clinic and completed additional assessments at home.
Two hundred and sixteen African American, Latino, and non-Latino white urban children, ages 7-9 years, and their primary caregivers.
Participants took part in a clinic assessment of asthma and allergy status, completed interview-based questionnaires including a diary to track asthma symptoms and sleep patterns, and used actigraphy and home-based spirometry daily across a 4-week period to assess sleep and lung function.
Results from analyses using structural equation modeling revealed an association between worsening asthma-related lung function and poor sleep quality in the full sample, as well as better asthma-related lung function at night and more optimal sleep efficiency that night. Ethnic group differences emerged in the association with morning or nighttime lung function measurements and sleep quality. Urban minority children with asthma may be at heightened risk for poorer quality sleep. Timing of lung function worsening may be important when considering when and how to improve both asthma health outcomes and sleep quality within specific groups.
（1）在一组患有持续性哮喘的城市儿童中，检查睡眠期间客观测量的哮喘相关肺功能（1 秒用力呼气量）变化与该睡眠期间的睡眠质量和睡眠时间之间的关系；（2）清晨和傍晚与哮喘相关的肺功能与相邻夜间的睡眠质量和睡眠时间之间的关系；（3）这些关联是否因种族群体而异。
横断面、多方法方法。儿童完成了哮喘和过敏状况的临床评估，并使用基于家庭的客观测量哮喘相关肺功能和睡眠。
儿童及其照顾者在哮喘和过敏诊所参加临床评估，并在家中完成额外的评估。
216 名非裔美国、拉丁裔和非拉丁裔白人城市儿童，年龄在 7-9 岁之间，以及他们的主要照顾者。
参与者参加了哮喘和过敏状况的临床评估，完成了基于访谈的问卷，包括日记以跟踪哮喘症状和睡眠模式，并在 4 周内每天使用活动记录仪和基于家庭的肺功能仪评估睡眠和肺功能。
使用结构方程模型进行的分析结果显示，在全样本中，哮喘相关肺功能恶化与睡眠质量差之间存在关联，以及夜间哮喘相关肺功能更好和当晚睡眠效率更高。在与清晨或夜间肺功能测量和睡眠质量相关的关联中出现了种族群体差异。患有哮喘的城市少数族裔儿童可能面临睡眠质量较差的风险增加。当考虑在特定群体中何时以及如何改善哮喘健康结果和睡眠质量时，肺功能恶化的时间可能很重要。
