Department of Psychology, Virginia Commonwealth University, Richmond, Virginia.
Bradley/Hasbro Children's Research Center, Alpert Medical School, Brown University, Providence, Rhode Island.
Ann Allergy Asthma Immunol. 2014 Apr;112(4):365-70.e1. doi: 10.1016/j.anai.2014.02.002. Epub 2014 Feb 28.
Urban children with asthma and allergic rhinitis (AR) are at risk for experiencing worse AR-related quality of life (QOL). Although AR may be underdiagnosed and undertreated in urban minority children, research has not considered which illness-related indicators (eg, AR control) may contribute to AR QOL in this population.
To examine associations among AR control, asthma control, allergy symptoms, asthma symptoms, and AR QOL in a sample of 195 urban caregivers and their children with asthma (7-9 years of age) from African American, Latino, and non-Latino white backgrounds. Racial and ethnic differences in AR QOL were also examined.
Families resided in 1 of 4 cities selected as recruitment sources because of their high concentrations of ethnic minority and non-Latino white, urban families. Caregivers and children completed a series of interview-based and clinician-based assessments across one academic year and 4-week periods to track daily asthma and nasal symptoms.
Better AR control was associated with higher AR QOL (β = -.32, P < .01) and all QOL subscales. AR control predicted AR QOL over and above asthma control (β = -.28, P < .01). Controlling for AR control, non-Latino white children reported better QOL related to practical problems than both Latino and African American children (P < .05).
Findings suggest that strategies to enhance AR control in urban children with asthma may assist in improving AR QOL. Non-Latino white children may experience less impairment of their AR QOL because of practical problems (eg, blow nose) than African American or Latino children with asthma.
患有哮喘和过敏性鼻炎（AR）的城市儿童患 AR 相关生活质量（QOL）下降的风险更高。尽管在城市少数民族儿童中，AR 可能被漏诊和治疗不足，但研究尚未考虑哪些与疾病相关的指标（例如，AR 控制）可能对该人群的 AR QOL 产生影响。
在一个由来自非裔美国、拉丁裔和非拉丁裔白人背景的哮喘患儿（7-9 岁）及其照顾者组成的样本中，研究 AR 控制、哮喘控制、过敏症状、哮喘症状与 AR QOL 之间的关联。还检查了 AR QOL 的种族和族裔差异。
家庭居住在 4 个城市中的 1 个，这些城市是根据其少数民族和非拉丁裔白人聚居的特点选择的招募来源。在一个学年和 4 周的时间里，照顾者和儿童完成了一系列基于访谈和基于临床医生的评估，以跟踪日常哮喘和鼻症状。
更好的 AR 控制与更高的 AR QOL（β=-.32，P<.01）和所有 QOL 子量表相关。控制哮喘控制后，非拉丁裔白人儿童在与实际问题相关的 QOL 上的报告优于拉丁裔和非裔美国儿童（P<.05）。
研究结果表明，在患有哮喘的城市儿童中增强 AR 控制的策略可能有助于改善 AR QOL。与患有哮喘的非裔美国或拉丁裔儿童相比，非拉丁裔白人儿童可能因实际问题（例如擤鼻涕）而对 AR QOL 的影响较小。
