Lam Phung Khanh, Fidler Sarah, Foster Caroline
Department of Infectious Diseases, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
900 Clinic, Department of HIV and GU Medicine, Imperial College Healthcare NHS Trust, London, UK.
J Int AIDS Soc. 2017 May 16;20(Suppl 3):21506. doi: 10.7448/IAS.20.4.21506.
Despite sharing common psychosocial and developmental experiences, adolescents living with perinatally and behaviourally acquired HIV-1 infection are different in terms of timing of HIV infection and developmental stage at infection. Therefore, it is of interest to identify similarities and differences between these two groups of adolescents living with HIV in their experiences, facilitators and barriers during the transition process.
A detailed literature search of peer-reviewed published papers was conducted on PubMed to identify relevant original research or viewpoints published up to September 2016. Conference abstracts and other unpublished data sources were not included.
Existing published literature, mainly using qualitative methods, explores the transition from paediatric to adult healthcare provision, as experienced by these two groups of young people. Reports highlight the variation and similarities in their experiences and challenges of transition. Findings from the USA and Europe predominate, while experience from Africa and Asia is lacking, despite the importance of these regions in the global epidemic.
Published transition data remain limited, and there are few studies focusing on behaviourally infected adolescents and key population groups (e.g. adolescents who use drugs, lesbian/gay/transgender individuals). Robust definitions of the transition process and standardized outcome measures are required to facilitate cross-study and geographic comparisons.
尽管围产期感染和行为感染HIV-1的青少年有着共同的心理社会和发育经历，但他们在HIV感染时间和感染时的发育阶段方面存在差异。因此，确定这两组感染HIV的青少年在过渡过程中的经历、促进因素和障碍的异同很有意义。
在PubMed上对同行评审的已发表论文进行了详细的文献检索，以确定截至2016年9月发表的相关原创研究或观点。会议摘要和其他未发表的数据来源未被纳入。
现有已发表的文献主要采用定性方法，探讨了这两组年轻人所经历的从儿科医疗到成人医疗的过渡。报告强调了他们在过渡经历和挑战方面的差异和相似之处。美国和欧洲的研究结果占主导地位，而非洲和亚洲的经验则缺乏，尽管这些地区在全球疫情中很重要。
已发表的过渡数据仍然有限，很少有研究关注行为感染的青少年和关键人群（如吸毒青少年、女同性恋/男同性恋/变性者）。需要对过渡过程进行明确的定义和标准化的结果测量，以促进跨研究和地域比较。
