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热疗可改善局部晚期乳腺癌的局部肿瘤控制。

Hyperthermia improves local tumour control in locally advanced breast cancer.

作者信息

Wiedemann G, Mella O, Coltart R S, Schem B C, Dahl O

机构信息

Department of Oncology, Haukeland Hospital, University of Bergen, Norway.

出版信息

Klin Wochenschr. 1988 Oct 17;66(20):1034-8. doi: 10.1007/BF01733451.

DOI:10.1007/BF01733451
PMID:2853249
Abstract

We report three patients with advanced breast cancer who received hyperthermia (43 degrees C over 1 h, weekly x 4) and radiotherapy as palliative treatment for chest-wall recurrence. The case reports demonstrate situations where hyperthermia may be beneficial. These include tumours where radiotherapy alone is not expected to achieve control, such as large fungating tumours, and in previously irradiated areas. In these patients, hyperthermia with radiation achieves better local control of the tumour and delays the need for systemic chemotherapy. This may improve the quality of palliation.

摘要

我们报告了3例晚期乳腺癌患者,她们接受了热疗(43摄氏度,持续1小时,每周1次,共4次)及放疗,作为胸壁复发的姑息性治疗。这些病例报告展示了热疗可能有益的情况。这些情况包括单独放疗预计无法实现控制的肿瘤,如巨大的溃疡性肿瘤,以及既往接受过放疗的区域。在这些患者中,热疗联合放疗能更好地实现肿瘤的局部控制,并延迟全身化疗的需求。这可能改善姑息治疗的质量。

相似文献

1
Hyperthermia improves local tumour control in locally advanced breast cancer.热疗可改善局部晚期乳腺癌的局部肿瘤控制。
Klin Wochenschr. 1988 Oct 17;66(20):1034-8. doi: 10.1007/BF01733451.
2
Local superficial hyperthermia in combination with low-dose radiation therapy for palliation of locally recurrent breast carcinoma.局部浅表热疗联合低剂量放射治疗用于缓解局部复发性乳腺癌。
J Clin Oncol. 1989 Jan;7(1):30-5. doi: 10.1200/JCO.1989.7.1.30.
3
Clinical results of thermoradiotherapy for locally advanced and/or recurrent breast cancer--comparison of results with radiotherapy alone.局部晚期和/或复发性乳腺癌热放疗的临床结果——与单纯放疗结果的比较
Int J Hyperthermia. 1990 May-Jun;6(3):487-97. doi: 10.3109/02656739009140945.
4
Hyperthermia and radiation therapy for locally advanced or recurrent breast cancer.局部晚期或复发性乳腺癌的热疗与放射治疗
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Local hyperthermia, radiation therapy, and chemotherapy in patients with local-regional recurrence of breast carcinoma.局部区域复发乳腺癌患者的局部热疗、放射治疗和化学治疗
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Re-irradiation of the chest wall for local breast cancer recurrence : Results of salvage brachytherapy with hyperthermia.局部乳腺癌复发后胸壁的再照射:热疗辅助挽救性近距离放射治疗的结果
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Arterial rupture after microwave-induced hyperthermia and radiotherapy. With reference to two patients treated for recurrence in previously operated and irradiated areas.微波诱导热疗和放疗后动脉破裂。参考两名在先前手术和放疗区域复发接受治疗的患者。
Int J Hyperthermia. 1990 May-Jun;6(3):499-509. doi: 10.3109/02656739009140946.
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[Re-irradiation with hyperthermia in patients with recurrent breast cancer].[复发性乳腺癌患者的热疗再照射]
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Prognosis of patients with locally recurrent breast cancer.局部复发性乳腺癌患者的预后
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引用本文的文献

1
Therapeutic strategies for fungating and ulcerating breast cancers: A systematic review and narrative synthesis.乳腺癌溃疡型和外生型的治疗策略:系统评价与叙述性综合分析
Breast. 2025 Feb;79:103870. doi: 10.1016/j.breast.2024.103870. Epub 2024 Dec 30.
2
Hyperthermia for locally advanced breast cancer.局部晚期乳腺癌的热疗。
Int J Hyperthermia. 2010;26(7):618-24. doi: 10.3109/02656736.2010.501051.

本文引用的文献

1
Thermotolerance: a review of observations and possible mechanisms.热耐受性:观察结果及可能机制的综述
Natl Cancer Inst Monogr. 1982 Jun;61:193-201.
2
Cancer of the breast: the past decade (first of two parts).乳腺癌:过去十年(两部分中的第一部分)
N Engl J Med. 1980 Jan 3;302(1):17-30. doi: 10.1056/NEJM198001033020104.
3
Hyperthermia for the engineer: a short biological primer.工程师眼中的热疗:简短的生物学入门知识
IEEE Trans Biomed Eng. 1984 Jan;31(1):3-8. doi: 10.1109/TBME.1984.325363.
4
The importance of thermotolerance for the clinical treatment with hyperthermia.热耐受性在热疗临床治疗中的重要性。
Radiother Oncol. 1983 Nov;1(2):167-78. doi: 10.1016/s0167-8140(83)80019-x.
5
Clinically derived dose effect relationship for hyperthermia given in combination with low dose radiotherapy.临床得出的热疗联合低剂量放疗的剂量效应关系。
Br J Radiol. 1985 Mar;58(687):243-50. doi: 10.1259/0007-1285-58-687-243.
6
Radiotherapy alone in breast cancer. I. Analysis of tumor parameters, tumor dose and local control: the experience of the Gustave-Roussy Institute and the Princess Margaret Hospital.乳腺癌单纯放疗。I. 肿瘤参数、肿瘤剂量及局部控制分析:古斯塔夫-鲁西研究所及玛格丽特公主医院的经验
Int J Radiat Oncol Biol Phys. 1985 Oct;11(10):1751-7. doi: 10.1016/0360-3016(85)90027-6.
7
Microwave-induced hyperthermia and radiotherapy in human superficial tumours: clinical results with a comparative study of combined treatment versus radiotherapy alone.微波诱导热疗与放疗用于人体浅表肿瘤:联合治疗与单纯放疗对比研究的临床结果
Int J Hyperthermia. 1987 Sep-Oct;3(5):393-411. doi: 10.3109/02656738709140410.
8
Clinical hyperthermia combined with drugs and radiation. A phase I/II study.
Strahlenther Onkol. 1987 Jul;163(7):446-8.
9
Problems in practical clinical hyperthermia: initial experience with the BSD-1000 system for local hyperthermia.临床实际热疗中的问题:使用BSD - 1000系统进行局部热疗的初步经验。
Strahlenther Onkol. 1987 Jul;163(7):436-8.
10
Site and disease selection for hyperthermia clinical trials.
Int J Hyperthermia. 1986 Apr-Jun;2(2):139-56. doi: 10.3109/02656738609012390.