[病毒性心肌炎和扩张型心肌病患者的干扰素系统指标]
[Indices of the interferon system in patients with viral myocarditis and dilated cardiomyopathy].
作者信息
Kipshidze N N, Chumburidze V B, Bakhutashvili V I, Korsantiia B M, Demetrashvili M F
出版信息
Ter Arkh. 1988;60(11):43-6.
The authors presented some data on the investigation of the interferon system in patients with dilatation cardiomyopathy (DCM) and viral myocarditis (VM). Diagnosis was verified according to the WHO criteria. Altogether 10 DCM patients and 24 VM patients with a grave course were investigated. Antibodies to Coxsackie B virus and influenza were detected in the VM patients. A decrease in the alpha- and gamma-interferon activity was shown in all DCM patients. The VM patients with a grave course also demonstrated a decrease in the alpha- and especially gamma-interferon (immune) activity. Methods of immune correction in such patients were discussed.
作者展示了一些关于扩张型心肌病（DCM）和病毒性心肌炎（VM）患者干扰素系统研究的数据。诊断依据世界卫生组织标准进行核实。共对10例DCM患者和24例病情严重的VM患者进行了调查。在VM患者中检测到了柯萨奇B病毒和流感病毒抗体。所有DCM患者均显示α干扰素和γ干扰素活性降低。病情严重的VM患者也表现出α干扰素尤其是γ干扰素（免疫）活性降低。文中讨论了此类患者的免疫纠正方法。
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