Isik Hatice, Isik Metin, Aynioglu Oner, Karcaaltincaba Deniz, Sahbaz Ahmet, Beyazcicek Tugba, Harma Mehmet Ibrahim, Demircan Nejat
Bulent Ecevit University, School of Medicine, Department of Obstetrics and Gynecology, Zonguldak, Turkey; Mevlana University, School of Medicine, Department of Obstetrics and Gynecology, Konya, Turkey.
Bulent Ecevit University, School of Medicine, Department of Rheumatology, Zonguldak, Turkey.
Rev Bras Reumatol Engl Ed. 2017 May-Jun;57(3):210-216. doi: 10.1016/j.rbre.2017.01.002. Epub 2017 Feb 8.
Females with Sjögren's Syndrome (SS) often experience vaginal dryness and dyspareunia, along with glandular and extraglandular symptoms. We aimed to evaluate sexual function and life quality in women with SS.
Forty-six premenopausal women with SS and 47 age-matched controls were studied. Age, duration of the disease, medications, and comorbid diseases were noted. Participants completed 36-Item Short Form Health Survey (SF-36) and Female Sexual Function Index (FSFI). Patients were asked about vaginal discharge and itching in the last month, and if they informed their rheumatologists about any sexual problems. Gynecologic examinations were performed and vaginal smears were taken on each participant.
The median total scores of FSFI were significantly lower in the SS group than the controls [17.12 (2.4-27.8) and 27.4 (16.9-36.0), respectively, p<0.001]. In the SS group, 37 (80.4%) and in the control group 18 (38.3%) of patients were sexually dissatisfied (p<0.001). Vaginal dryness and lubricant use were significantly increased in patients with SS compared to controls (p<0.001). Life quality scores were significantly lower in patients with SS than the controls (p<0.001). Vaginal dryness was negatively correlated with FSFI total (r=-0.312, p=0.035) and subscores except desire and arousal. Physical functioning, role physical and role emotional scores were positively correlated with total FSFI scores (r=0.449, p=0.002, r=0.371, p=0.011, r=0.299, p=0.043, respectively).
Women with SS experience less satisfaction with sexual activity, which can be affected by age, vaginal dryness, physical pain, and impaired function due to the disease. Therefore, rheumatologists should pay attention to these symptoms and management.
干燥综合征（SS）女性常出现阴道干燥和性交困难，伴有腺体及腺体外症状。我们旨在评估SS女性的性功能和生活质量。
对46名绝经前SS女性和47名年龄匹配的对照者进行研究。记录年龄、病程、用药情况及合并疾病。参与者完成36项简短健康调查（SF - 36）和女性性功能指数（FSFI）。询问患者过去一个月的阴道分泌物及瘙痒情况，以及是否向风湿病医生告知过任何性问题。对每位参与者进行妇科检查并采集阴道涂片。
SS组FSFI总分中位数显著低于对照组[分别为17.12（2.4 - 27.8）和27.4（16.9 - 36.0），p<0.001]。SS组中37名（80.4%）患者对性生活不满意，对照组中为18名（38.3%）（p<0.001）。与对照组相比，SS患者的阴道干燥及润滑剂使用显著增加（p<0.001）。SS患者的生活质量得分显著低于对照组（p<0.001）。阴道干燥与FSFI总分（r = -0.312，p = 0.035）及除欲望和唤起外的子得分呈负相关。身体功能、角色身体和角色情感得分与FSFI总分呈正相关（分别为r = 0.449，p = 0.002；r = 0.371，p = 0.011；r = 0.299，p = 0.043）。
SS女性对性活动的满意度较低，这可能受到年龄、阴道干燥、身体疼痛及疾病导致的功能受损影响。因此，风湿病医生应关注这些症状及处理。
