Soltani Mehdi, Baldisserotto Bernardo, Hosseini Shekarabi Seyed Pezhman, Shafiei Shafigh, Bashiri Masoumeh
Freshwater Fish Group and Fish Health Unit, Centre for Sustainable Aquatic Ecosystems, Harry Butler Institute, Murdoch University, Murdoch, Perth, WA 6150, Australia.
Department of Aquatic Animal Health, Faculty of Veterinary Medicine, University of Tehran, Tehran 1419963111, Iran.
Vet Sci. 2021 Sep 3;8(9):181. doi: 10.3390/vetsci8090181.
Lactococcosis, particularly that caused by , is a major re-emerging bacterial disease seriously affecting the sustainability of aquaculture industry. Medicinal herbs and plants do not have very much in vitro antagonism and in vivo disease resistance towards lactococcosis agents in aquaculture. Most in vitro studies with herbal extractives were performed against with no strong antibacterial activity, but essential oils, especially those that contain thymol or carvacrol, are more effective. The differences exhibited by the bacteriostatic and bactericidal functions for a specific extractive in different studies could be due to different bacterial strains or parts of chemotypes of the same plant. Despite essential oils being shown to have the best anti- activity in in vitro assays, the in vivo bioassays required further study. The extracts tested under in vivo conditions presented moderate efficacy, causing a decrease in mortality in infected animals, probably because they improved immune parameters before challenging tests. This review addressed the efficacy of medicinal herbs to lactococcosis and discussed the presented gaps.
乳球菌病，尤其是由[具体病菌未给出]引起的乳球菌病，是一种重新出现的主要细菌性疾病，严重影响水产养殖业的可持续性。药草和植物对水产养殖中的乳球菌病病原体在体外拮抗作用和体内抗病性方面作用不大。大多数关于草药提取物的体外研究是针对[具体病菌未给出]进行的，且没有很强的抗菌活性，但精油，尤其是含有百里香酚或香芹酚的精油，效果更佳。在不同研究中，特定提取物的抑菌和杀菌功能表现出的差异可能是由于不同的细菌菌株或同一植物化学型的不同部分。尽管精油在体外试验中显示出最佳的抗[病菌名称未明确]活性，但体内生物测定仍需进一步研究。在体内条件下测试的提取物表现出中等疗效，使感染动物的死亡率降低，这可能是因为它们在攻毒试验前改善了免疫参数。本综述阐述了药草对乳球菌病的疗效，并讨论了存在的差距。
