Wang Yu-Bo, Su Shan-Shan, Chen Shao-Fei, Tang Ming-Xu, Chen Gang, Zhao Dan, Sang Xia-Nan, Si Ying-Ying, Wang Hai-Feng, Pei Yue-Hu
a School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University , Shenyang 110016 , China.
b Key Laboratory of Structure-Based Drug Design and Discovery , Ministry of Education, Shenyang Pharmaceutical University , Shenyang 110016 , China.
J Asian Nat Prod Res. 2018 Mar;20(3):263-269. doi: 10.1080/10286020.2017.1329302. Epub 2017 May 24.
Two new C steroidal glycosides, cynataihosides E (1) and F (2), together with a known one, sublanceoside H (3), were isolated from Cynanchum taihangense. The aglycone of cynataihoside F (2) was also a new compound. Their structures were elucidated on the basis of NMR spectroscopic data, HR-ESI-MS analysis, and chemical evidence. Their cytotoxic activities against three human tumor cell lines (HL-60, THP1, and Caco2) were reported.
从太行白前（Cynanchum taihangense）中分离出两种新的C甾体糖苷，太行白前苷E（1）和F（2），以及一种已知的化合物，次矛叶白前苷H（3）。太行白前苷F（2）的苷元也是一种新化合物。基于核磁共振光谱数据、高分辨电喷雾电离质谱分析和化学证据阐明了它们的结构。报道了它们对三种人类肿瘤细胞系（HL-60、THP1和Caco2）的细胞毒性活性。
