State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University , Nanjing 210096, China.
Chem Rev. 2017 Jun 28;117(12):7964-8040. doi: 10.1021/acs.chemrev.6b00848. Epub 2017 May 24.
Droplet microfluidics generates and manipulates discrete droplets through immiscible multiphase flows inside microchannels. Due to its remarkable advantages, droplet microfluidics bears significant value in an extremely wide range of area. In this review, we provide a comprehensive and in-depth insight into droplet microfluidics, covering fundamental research from microfluidic chip fabrication and droplet generation to the applications of droplets in bio(chemical) analysis and materials generation. The purpose of this review is to convey the fundamentals of droplet microfluidics, a critical analysis on its current status and challenges, and opinions on its future development. We believe this review will promote communications among biology, chemistry, physics, and materials science.
液滴微流控技术通过在微通道内的不混相多相流来生成和操纵离散液滴。由于其显著的优势，液滴微流控技术在极其广泛的领域具有重要价值。在这篇综述中，我们对液滴微流控技术进行了全面而深入的了解，涵盖了从微流控芯片制造和液滴生成到液滴在生物（化学）分析和材料生成中的应用的基础研究。本综述的目的是传达液滴微流控技术的基础知识，对其现状和挑战进行批判性分析，并对其未来发展提出意见。我们相信，这篇综述将促进生物学、化学、物理学和材料科学之间的交流。
