Center of Bio-Medical Research, Division of Molecular Synthesis & Drug Discovery, SGPGIMS Campus , Raebareli Road, Lucknow 226014, Uttar Pradesh, India.
J Am Chem Soc. 2017 Jun 14;139(23):7745-7748. doi: 10.1021/jacs.7b04490. Epub 2017 Jun 2.
An efficient strategy for the para-selective borylation of aromatic esters is described. For achieving high para-selectivity, a new catalytic system has been developed modifying the core structure of the bipyridine. It has been proposed that the L-shaped ligand is essential to recognize the functionality of the oxygen atom of the ester carbonyl group via noncovalent interaction, which provides an unprecedented controlling factor for para-selective C-H activation/borylation.
描述了一种用于芳基酯的对选择性硼化的有效策略。为了实现高对选择性，通过修饰双吡啶的核心结构开发了新的催化体系。据提出，L 形配体对于通过非共价相互作用识别酯羰基氧原子的官能团是必不可少的，这为对选择性 C-H 活化/硼化提供了前所未有的控制因素。
