Jemec Gregor Be
Deptartment of Dermatology, Zealand University Hospital, Roskilde, and Health Sciences Faculty, University of Copenhagen, Denmark.
Semin Cutan Med Surg. 2017 Jun;36(2):75-78. doi: 10.12788/j.sder.2017.016.
All skin diseases involve some element of stigmatization and psychosocial consequence for the individual patient, but few, if any, skin diseases can match the impact of hidradenitis suppurativa (HS) on the patient. The inflamed lesions progressing to noninflamed nodules and abscesses are not only perceived as unclean and stigmatizing by the patients, but also cause pain and scarring making this inflammatory skin disorder unique. It is obvious that the disease has a significant negative impact on the patients' quality of life (QOL). The impact is influenced not only by the pain which is a significant independent contributor to the patients' life quality, but by the clinically significant comorbidity associated with HS. In particular, the psychological comorbidities of depression and anxiety both further compound QOL impairment and pain. It is strongly recommended that these factors be taken into account when planning a treatment strategy for patients with HS, and that specific steps are taken to manage pain and comorbidities associated with the reduced QOL generally experienced by this group of patients. Basic pain management includes anti-inflammatory treatments as well as local- and central-acting analgesics. In more complex cases, access to consultations with a pain specialist may be necessary and may require the judicious use of antidepressants. In addition, it is recommended that patients' QOL be addressed specifically through psychological education and patient support groups.
所有皮肤病都会给患者个人带来一定程度的污名化和心理社会影响,但很少有皮肤病(如果有的话)能与化脓性汗腺炎(HS)对患者的影响相匹敌。炎症性病变发展为非炎症性结节和脓肿,不仅会让患者觉得不洁净且有污名感,还会导致疼痛和瘢痕形成,使这种炎症性皮肤病独具特点。显然,该疾病对患者的生活质量(QOL)有重大负面影响。这种影响不仅受疼痛(这是影响患者生活质量的一个重要独立因素)的影响,还受与HS相关的具有临床意义的合并症的影响。特别是,抑郁和焦虑等心理合并症会进一步加重生活质量受损和疼痛。强烈建议在为HS患者制定治疗策略时考虑这些因素,并采取具体措施来管理与该组患者普遍经历的生活质量下降相关的疼痛和合并症。基本的疼痛管理包括抗炎治疗以及局部和中枢作用的镇痛药。在更复杂的情况下,可能需要咨询疼痛专家,可能还需要谨慎使用抗抑郁药。此外,建议通过心理教育和患者支持小组专门解决患者的生活质量问题。