• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

化脓性汗腺炎:对发病机制的当前认识及治疗方案建议

Hidradenitis Suppurativa: Current Understanding of Pathogenic Mechanisms and Suggestion for Treatment Algorithm.

作者信息

Seyed Jafari S Morteza, Hunger Robert E, Schlapbach Christoph

机构信息

Department of Dermatology, Inselspital, Bern University Hospital, Bern, Switzerland.

出版信息

Front Med (Lausanne). 2020 Mar 4;7:68. doi: 10.3389/fmed.2020.00068. eCollection 2020.

DOI:10.3389/fmed.2020.00068
PMID:32195261
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7064439/
Abstract

Hidradenitis suppurativa is one of the most distressing dermatological conditions and has a significant negative impact on patients' quality of life. However, the exact pathogenic mechanisms remain incompletely understood and-therefore-efficient therapies are still lacking. The current manuscript focuses on new findings on its pathogenic mechanisms and aims to provide practical therapy recommendations.

摘要

化脓性汗腺炎是最令人苦恼的皮肤病之一,对患者的生活质量有重大负面影响。然而,其确切的致病机制仍未完全明确,因此仍然缺乏有效的治疗方法。本手稿重点关注其致病机制的新发现,并旨在提供实用的治疗建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b965/7064439/06ebb942054c/fmed-07-00068-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b965/7064439/06ebb942054c/fmed-07-00068-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b965/7064439/06ebb942054c/fmed-07-00068-g0001.jpg

相似文献

1
Hidradenitis Suppurativa: Current Understanding of Pathogenic Mechanisms and Suggestion for Treatment Algorithm.化脓性汗腺炎:对发病机制的当前认识及治疗方案建议
Front Med (Lausanne). 2020 Mar 4;7:68. doi: 10.3389/fmed.2020.00068. eCollection 2020.
2
Comparative Study of Quality of Life and Psychological Aspects in Patients with Psoriasis and Hidradenitis Suppurativa.银屑病和化脓性汗腺炎患者生活质量和心理方面的对比研究。
Acta Dermatovenerol Croat. 2021 Nov;29(4):203-210.
3
Body Image Quality of Life in Patients with Hidradenitis Suppurativa Compared with Other Dermatological Disorders.化脓性汗腺炎患者的身体意象生活质量与其他皮肤科疾病的比较。
Acta Derm Venereol. 2020 Apr 6;100(8):adv00107. doi: 10.2340/00015555-3464.
4
Two Cases of Hidradenitis Suppurativa Treated with Adalimumab at the Department of Dermatology and Venereology, Clinical Hospital Mostar.皮肤科和性病科在莫斯塔尔临床医院用阿达木单抗治疗两例化脓性汗腺炎。
Acta Dermatovenerol Croat. 2021 Jul;29(2):108-110.
5
The role of interleukin-17 in the pathogenesis of hidradenitis suppurativa.白细胞介素-17在化脓性汗腺炎发病机制中的作用。
Dermatol Online J. 2017 Jul 15;23(7):13030/qt8rw2j9zv.
6
Correlation between Depression, Quality of Life and Clinical Severity in Patients with Hidradenitis Suppurativa.化脓性汗腺炎患者抑郁、生活质量与临床严重程度之间的相关性
Acta Derm Venereol. 2020 Nov 12;100(18):adv00319. doi: 10.2340/00015555-3647.
7
Major gaps in understanding and treatment of hidradenitis suppurativa.化脓性汗腺炎在认识和治疗方面的重大差距。
Semin Cutan Med Surg. 2017 Jun;36(2):86-92. doi: 10.12788/j.sder.2017.024.
8
Concomitant psoriasis and hidradenitis suppurativa responsive to adalimumab therapy: A case series.阿达木单抗治疗伴发银屑病和化脓性汗腺炎有效:一组病例报告。
Indian J Dermatol Venereol Leprol. 2021 Mar-Apr;87(2):223-226. doi: 10.4103/ijdvl.IJDVL_455_18.
9
Pyoderma Gangrenosum, Acne, and Hidradenitis Suppurativa Syndrome: A Case Report and Literature Review.坏疽性脓皮病、痤疮和化脓性汗腺炎综合征:一例报告及文献综述
Front Med (Lausanne). 2022 Mar 24;9:856786. doi: 10.3389/fmed.2022.856786. eCollection 2022.
10
Hidradenitis Suppurativa: Absence of Hyperhidrosis but Presence of a Proinflammatory Signature in Patients' Sweat.化脓性汗腺炎:患者汗液中无多汗症但存在促炎特征。
Acta Derm Venereol. 2022 Oct 18;102:adv00793. doi: 10.2340/actadv.v102.2731.

引用本文的文献

1
Prevalence of Hidradenitis Suppurativa in Fars Province, Iran.伊朗法尔斯省化脓性汗腺炎的患病率
Dermatology. 2025 Jul 7:1-6. doi: 10.1159/000540422.
2
The impact of innate immunity and epigenetics in the pathogenesis of hidradenitis suppurativa.先天性免疫和表观遗传学在化脓性汗腺炎发病机制中的作用
Front Immunol. 2025 May 19;16:1593253. doi: 10.3389/fimmu.2025.1593253. eCollection 2025.
3
A systematic review of tumor necrosis factor-α blockers, anti-interleukins, and small molecule inhibitors for dissecting cellulitis of the scalp treatment.

本文引用的文献

1
Neutrophil extracellular traps, B cells, and type I interferons contribute to immune dysregulation in hidradenitis suppurativa.中性粒细胞胞外陷阱、B 细胞和 I 型干扰素导致化脓性汗腺炎的免疫失调。
Sci Transl Med. 2019 Sep 4;11(508). doi: 10.1126/scitranslmed.aav5908.
2
Intralesional corticosteroid injection for the treatment of hidradenitis suppurativa: a multicenter retrospective clinical study.皮损内注射皮质类固醇治疗化脓性汗腺炎:一项多中心回顾性临床研究。
J Dermatolog Treat. 2021 May;32(3):286-290. doi: 10.1080/09546634.2019.1655524. Epub 2019 Aug 29.
3
Systematic review of immunomodulatory therapies for hidradenitis suppurativa.
一项关于肿瘤坏死因子-α阻滞剂、抗白细胞介素和小分子抑制剂用于治疗头皮蜂窝织炎的系统评价。
Orphanet J Rare Dis. 2025 May 18;20(1):236. doi: 10.1186/s13023-025-03720-5.
4
The Inflammatory Landscape of a Whole-Tissue Explant Model of Hidradenitis Suppurativa.化脓性汗腺炎全组织外植体模型的炎症图谱
Exp Dermatol. 2025 Feb;34(2):e70057. doi: 10.1111/exd.70057.
5
Marginal Zone Lymphoma in a Case of Hidradenitis Suppurativa Treated With Adalimumab Therapy.用阿达木单抗治疗的化脓性汗腺炎患者中的边缘区淋巴瘤
J Community Hosp Intern Med Perspect. 2025 Jan 6;15(1):58-62. doi: 10.55729/2000-9666.1444. eCollection 2025.
6
Unlocking the Mechanisms of Hidradenitis Suppurativa: Inflammation and miRNA Insights.揭开化脓性汗腺炎的发病机制:炎症与微小RNA的见解
Clin Cosmet Investig Dermatol. 2024 Dec 11;17:2829-2846. doi: 10.2147/CCID.S483871. eCollection 2024.
7
Hidradenitis Suppurativa: A Review of the Biologic and Small Molecule Immunomodulatory Treatments.化脓性汗腺炎:生物制剂和小分子免疫调节治疗综述
J Cutan Med Surg. 2025 Jan-Feb;29(1):NP1-NP20. doi: 10.1177/12034754241300292. Epub 2024 Nov 27.
8
IgG4 serologic elevation in a patient with severe hidradenitis suppurativa: a case report and review of the literature.重度化脓性汗腺炎患者的IgG4血清学升高:一例病例报告及文献复习
Front Med (Lausanne). 2024 Oct 11;11:1471226. doi: 10.3389/fmed.2024.1471226. eCollection 2024.
9
A Case of Hidradenitis Suppurativa Responsive to Testosterone Replacement Therapy.一例对睾酮替代疗法有反应的化脓性汗腺炎病例。
Indian Dermatol Online J. 2024 Aug 19;15(5):854-855. doi: 10.4103/idoj.idoj_653_23. eCollection 2024 Sep-Oct.
10
Assessing the Role of Adalimumab in Treating Hidradenitis Suppurativa: Findings from a Retrospective Study at a Reference Center.评估阿达木单抗在治疗化脓性汗腺炎中的作用:来自一家参考中心的回顾性研究结果。
Clin Pract. 2024 Aug 27;14(5):1696-1706. doi: 10.3390/clinpract14050135.
化脓性汗腺炎免疫调节疗法的系统评价
Biologics. 2019 May 13;13:53-78. doi: 10.2147/BTT.S199862. eCollection 2019.
4
North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part I: Diagnosis, evaluation, and the use of complementary and procedural management.北美化脓性汗腺炎临床管理指南:美国和加拿大化脓性汗腺炎基金会的出版物:第一部分:诊断、评估和补充及程序管理的应用。
J Am Acad Dermatol. 2019 Jul;81(1):76-90. doi: 10.1016/j.jaad.2019.02.067. Epub 2019 Mar 11.
5
North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part II: Topical, intralesional, and systemic medical management.北美化脓性汗腺炎临床管理指南:美国和加拿大化脓性汗腺炎基金会联合发布:第二部分:局部、皮损内和全身医学治疗。
J Am Acad Dermatol. 2019 Jul;81(1):91-101. doi: 10.1016/j.jaad.2019.02.068. Epub 2019 Mar 11.
6
Transcriptome patterns in hidradenitis suppurativa: support for the role of antimicrobial peptides and interferon pathways in disease pathogenesis.化脓性汗腺炎转录组图谱:支持抗菌肽和干扰素通路在疾病发病机制中的作用。
Clin Exp Dermatol. 2019 Dec;44(8):882-892. doi: 10.1111/ced.13959. Epub 2019 Apr 24.
7
A systematic review and critical evaluation of inflammatory cytokine associations in hidradenitis suppurativa.化脓性汗腺炎中炎症细胞因子关联的系统评价与批判性评估
F1000Res. 2018 Dec 13;7:1930. doi: 10.12688/f1000research.17267.1. eCollection 2018.
8
Abstracts of the 8th European Hidradenitis Suppurativa Foundation (EHSF) Conference, 6-8 February 2019, Wrocław, Poland.第八届欧洲化脓性汗腺炎基金会(EHSF)会议摘要,2019年2月6日至8日,波兰弗罗茨瓦夫
Exp Dermatol. 2019 Feb;28 Suppl 2:5-55. doi: 10.1111/exd.13893.
9
Bacterial biofilm is associated with higher levels of regulatory T cells in unaffected hidradenitis suppurativa skin.细菌生物膜与未受影响的化脓性汗腺炎皮肤中调节性 T 细胞水平升高有关。
Exp Dermatol. 2019 Mar;28(3):312-316. doi: 10.1111/exd.13885.
10
Guselkumab in the treatment of hidradenitis suppurativa: A retrospective chart review.古塞库单抗治疗化脓性汗腺炎:一项回顾性病历审查。
J Am Acad Dermatol. 2019 Jul;81(1):265-267. doi: 10.1016/j.jaad.2018.12.017. Epub 2018 Dec 15.