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白色星爆样图案作为旧大陆皮肤利什曼病的皮肤镜线索

White starburst-like pattern as a dermoscopic clue in Old World cutaneous leishmaniasis.

作者信息

Fernandez-Crehuet Pablo, Ruiz-Villaverde Ricardo

机构信息

Dermatology Department. Hospital Universitario Reina Sofía - Cordoba, Spain.

Instituto Maimónides de Investigación Biomédica (IMIBIC) - Cordoba. Spain.

出版信息

An Bras Dermatol. 2017 Mar-Apr;92(2):266-267. doi: 10.1590/abd1806-4841.20175728.

DOI:10.1590/abd1806-4841.20175728
PMID:28538895
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5429121/
Abstract

A 70-year-old woman was referred to our dermatological unit by her general practitioner last summer, with a history of a two-month ulcerated purplish lesion on her left arm that spread centrifugally and that unsuccessfully treated with topical corticosteroids. The dermoscopic evaluation revealed an erythematous macula with central ulceration that showed the characteristic called "white starburst-like pattern" and some vascular structures (dotted vessels, polymorphous⁄ atypical vessels). The diagnosis of cutaneous leishmaniasis was made after histopathologic analysis and polymerase chain reaction essay.

摘要

去年夏天,一名70岁女性被她的全科医生转诊至我们的皮肤科,她的左臂有一个两个月大的溃疡紫色病变,呈离心性扩散,外用皮质类固醇治疗无效。皮肤镜检查显示为中央溃疡的红斑,具有“白色星爆样图案”的特征以及一些血管结构(点状血管、多形性/非典型血管)。经组织病理学分析和聚合酶链反应检测后确诊为皮肤利什曼病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a1d/5429121/f1247d3031a1/abd-92-02-0266-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a1d/5429121/d1ed23a5e475/abd-92-02-0266-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a1d/5429121/7643612b0214/abd-92-02-0266-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a1d/5429121/f1247d3031a1/abd-92-02-0266-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a1d/5429121/d1ed23a5e475/abd-92-02-0266-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a1d/5429121/7643612b0214/abd-92-02-0266-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a1d/5429121/f1247d3031a1/abd-92-02-0266-g03.jpg

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本文引用的文献

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A 45 year old man with an ulcerated nodule on his right leg.一名45岁男性,右腿有一个溃疡结节。
BMJ. 2014 Sep 8;349:g5296. doi: 10.1136/bmj.g5296.
2
Therapeutic options for old world cutaneous leishmaniasis and new world cutaneous and mucocutaneous leishmaniasis.旧世界皮肤利什曼病和新世界皮肤和黏膜利什曼病的治疗选择。
Drugs. 2013 Nov;73(17):1889-920. doi: 10.1007/s40265-013-0132-1.
3
Direct diagnosis of Leishmania species on serosity materials punctured from cutaneous leishmaniasis patients using PCR-RFLP.应用 PCR-RFLP 技术直接检测皮肤利什曼病患者穿刺浆膜液中的利什曼原虫种属。
J Clin Lab Anal. 2011;25(1):20-4. doi: 10.1002/jcla.20377.
4
Current diagnosis and treatment of cutaneous and mucocutaneous leishmaniasis.皮肤和黏膜利什曼病的当前诊断和治疗。
Expert Rev Anti Infect Ther. 2010 Apr;8(4):419-33. doi: 10.1586/eri.10.19.
5
Dermoscopy of cutaneous leishmaniasis.皮肤利什曼病的皮肤镜检查
Br J Dermatol. 2009 Apr;160(4):756-61. doi: 10.1111/j.1365-2133.2008.08986.x. Epub 2008 Dec 16.
6
Detection and identification of Leishmania species from clinical specimens by using a real-time PCR assay and sequencing of the cytochrome B gene.通过实时聚合酶链反应分析及细胞色素B基因测序从临床标本中检测和鉴定利什曼原虫种类。
J Clin Microbiol. 2007 Jul;45(7):2110-5. doi: 10.1128/JCM.02555-06. Epub 2007 May 2.
7
[Cutaneous leishmaniasis].[皮肤利什曼病]
Actas Dermosifiliogr. 2005 Jan-Feb;96(1):1-24. doi: 10.1016/s0001-7310(05)73027-1.
8
Value of diagnostic techniques for cutaneous leishmaniasis.皮肤利什曼病诊断技术的价值。
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