Wielosz Ewa, Kurowska Maria, Suszek Dorota, Majdan Maria
Department of Rheumatology and Connective Tissue Diseases, Medical University, Lublin, Poland.
Department of Endocrynology, Medical University, Lublin, Poland.
Reumatologia. 2017;55(2):104-107. doi: 10.5114/reum.2017.67607. Epub 2017 Apr 28.
Diabetic sclerodactyly is a frequently recognized skin finding that may occur in patients with diabetes mellitus but coexistence of diabetes and systemic sclerosis is rare. We describe a case of coexistence of type 1 diabetes mellitus and systemic sclerosis in 42-year-old man with the history of Raynaud's phenomenon, progressive diffuse hardening of the skin and sclerodactyly, slowly worsening with time. The medical history included type 1 diabetes since childhood with microvascular complications. The patient presented a typical capillaroscopic scleroderma-like pattern, antinuclear antibodies and sclerotic lesions in gastrointestinal system. Summing up, our case represents the rare coexistence of autoimmune diseases like diabetes mellitus type 1 and systemic sclerosis.
糖尿病性硬皮病是一种常见的皮肤表现,可发生于糖尿病患者,但糖尿病与系统性硬化症并存的情况较为罕见。我们报告一例42岁男性,患有1型糖尿病和系统性硬化症,有雷诺现象、皮肤进行性弥漫性硬化及硬皮病样改变病史,且病情随时间缓慢加重。病史包括自幼患1型糖尿病并伴有微血管并发症。该患者呈现典型的毛细血管镜下硬皮病样表现、抗核抗体及胃肠道硬化性病变。总之,我们的病例代表了1型糖尿病和系统性硬化症等自身免疫性疾病的罕见并存情况。