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技术微生物学:发展与应用

Technological Microbiology: Development and Applications.

作者信息

Vitorino Luciana C, Bessa Layara A

机构信息

Laboratory of Agricultural Microbiology, Goiano Federal InstituteGoiás, Brazil.

出版信息

Front Microbiol. 2017 May 10;8:827. doi: 10.3389/fmicb.2017.00827. eCollection 2017.

Abstract

Over thousands of years, modernization could be predicted for the use of microorganisms in the production of foods and beverages. However, the current accelerated pace of new food production is due to the rapid incorporation of biotechnological techniques that allow the rapid identification of new molecules and microorganisms or even the genetic improvement of known species. At no other time in history have microorganisms been so present in areas such as agriculture and medicine, except as recognized villains. Currently, however, beneficial microorganisms such as plant growth promoters and phytopathogen controllers are required by various agricultural crops, and many species are being used as biofactories of important pharmacological molecules. The use of biofactories does not end there: microorganisms have been explored for the synthesis of diverse chemicals, fuel molecules, and industrial polymers, and strains environmentally important due to their biodecomposing or biosorption capacity have gained interest in research laboratories and in industrial activities. We call this new microbiology Technological Microbiology, and we believe that complex techniques, such as heterologous expression and metabolic engineering, can be increasingly incorporated into this applied science, allowing the generation of new and improved products and services.

摘要

数千年来,可以预见微生物会被用于食品和饮料的生产。然而,当前新食品生产加速的步伐是由于生物技术的迅速融入,这些技术能够快速识别新分子和微生物,甚至对已知物种进行基因改良。在历史上的任何其他时期,微生物在农业和医学等领域都没有像现在这样普遍存在,除非它们被视为公认的有害生物。然而目前,各种农作物都需要有益微生物,如植物生长促进剂和植物病原体控制剂,而且许多物种正被用作重要药理分子的生物工厂。生物工厂的用途还不止于此:微生物已被探索用于合成各种化学品、燃料分子和工业聚合物,并且因其生物分解或生物吸附能力而对环境具有重要意义的菌株已引起研究实验室和工业活动的关注。我们将这种新的微生物学称为技术微生物学,并且我们相信诸如异源表达和代谢工程等复杂技术能够越来越多地融入这一应用科学,从而能够生产出新的和改良的产品及服务。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c48/5423913/f799bb9ca849/fmicb-08-00827-g001.jpg

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