结核性脑膜炎被误诊为单纯疱疹病毒1型脑炎且采用FilmArray综合征聚合酶链反应检测板导致诊断延迟
Delayed Diagnosis of Tuberculous Meningitis Misdiagnosed as Herpes Simplex Virus-1 Encephalitis With the FilmArray Syndromic Polymerase Chain Reaction Panel.
作者信息
Gomez Carlos A, Pinsky Benjamin A, Liu Anne, Banaei Niaz
机构信息
Division of Infectious Diseases and Geographic Medicine, Department of Medicine.
Department of Pathology, and.
出版信息
Open Forum Infect Dis. 2016 Dec 7;4(1):ofw245. doi: 10.1093/ofid/ofw245. eCollection 2017 Winter.
Abstract
The FilmArray meningitis/encephalitis (ME) panel is a novel syndromic, nucleic acid amplification test for diagnosis of acute meningitis and encephalitis. Emerging data on its performance are concerning for false-positive results. We present a case of tuberculous meningitis misdiagnosed as herpes simplex virus-1 encephalitis with the FilmArray ME panel. Strategies to mitigate erroneous results are discussed.
摘要
FilmArray脑膜炎/脑炎（ME）检测板是一种用于诊断急性脑膜炎和脑炎的新型综合征核酸扩增检测方法。关于其性能的新数据令人担忧其可能出现假阳性结果。我们报告一例结核性脑膜炎被FilmArray ME检测板误诊为单纯疱疹病毒1型脑炎的病例。并讨论了减少错误结果的策略。
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