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使用胆碱和PSMA PET/CT对前列腺癌进行治疗评估。

Therapy assessment in prostate cancer using choline and PSMA PET/CT.

作者信息

Ceci Francesco, Herrmann Ken, Hadaschik Boris, Castellucci Paolo, Fanti Stefano

机构信息

Nuclear Medicine Unit, S. Orsola-Malpighi University Hospital, University of Bologna, Via Massarenti, 9, 40138, Bologna, Italy.

Department of Nuclear Medicine, University Hospital Essen, Essen, Germany.

出版信息

Eur J Nucl Med Mol Imaging. 2017 Aug;44(Suppl 1):78-83. doi: 10.1007/s00259-017-3723-3. Epub 2017 May 25.

DOI:10.1007/s00259-017-3723-3
PMID:28540419
Abstract

While PET with non-FDG tracers (mainly choline and Ga-PSMA) has commonly been used for restaging in men with biochemically recurrent prostate cancer, as well as for primary staging, it is only recently that a few preliminary studies have addressed the possible use of PET for monitoring the response to systemic therapy of metastatic disease, especially innovative treatments such as abiraterone and enzalutamide. This article aims to evaluate the role of PET imaging with different non-FDG radiotracers for assessment of therapy in advanced prostate cancer patients.

摘要

虽然使用非氟代脱氧葡萄糖(FDG)示踪剂(主要是胆碱和镓-前列腺特异性膜抗原[Ga-PSMA])的正电子发射断层扫描(PET)通常用于对生化复发前列腺癌男性患者进行再分期以及原发性分期,但直到最近才有一些初步研究探讨了PET在监测转移性疾病全身治疗反应,尤其是阿比特龙和恩杂鲁胺等创新治疗反应方面的可能用途。本文旨在评估使用不同非FDG放射性示踪剂的PET成像在评估晚期前列腺癌患者治疗中的作用。

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本文引用的文献

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Ga-PSMA PET/CT: Joint EANM and SNMMI procedure guideline for prostate cancer imaging: version 1.0.镓-前列腺特异性膜抗原正电子发射断层显像/计算机断层扫描:欧洲核医学协会和美国核医学与分子影像学会联合发布的前列腺癌成像程序指南:第1.0版
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Multisite Experience of the Safety, Detection Rate and Diagnostic Performance of Fluciclovine (F) Positron Emission Tomography/Computerized Tomography Imaging in the Staging of Biochemically Recurrent Prostate Cancer.多中心研究:氟脱氧葡萄糖(18F)正电子发射断层扫描/计算机断层扫描成像在生化复发前列腺癌分期中的安全性、检出率和诊断性能。
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PSMA和胆碱PET用于评估前列腺癌患者的治疗反应和生存结果:文献系统评价
Cancers (Basel). 2022 Mar 31;14(7):1770. doi: 10.3390/cancers14071770.
4
Targeting PSMA Revolutionizes the Role of Nuclear Medicine in Diagnosis and Treatment of Prostate Cancer.靶向前列腺特异性膜抗原(PSMA)彻底改变了核医学在前列腺癌诊断和治疗中的作用。
Cancers (Basel). 2022 Feb 24;14(5):1169. doi: 10.3390/cancers14051169.
5
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EJNMMI Res. 2019 Aug 29;9(1):84. doi: 10.1186/s13550-019-0554-1.
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Eur Urol. 2017 Apr;71(4):618-629. doi: 10.1016/j.eururo.2016.08.003. Epub 2016 Aug 25.
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Eur Urol. 2017 Jan;71(1):81-92. doi: 10.1016/j.eururo.2016.05.033. Epub 2016 Jun 14.
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Future Oncol. 2016 Feb;12(3):333-42. doi: 10.2217/fon.15.277. Epub 2016 Jan 15.
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Repeatability of Quantitative 18F-Fluoromethylcholine PET/CT Studies in Prostate Cancer.18F-氟甲基胆碱PET/CT定量研究在前列腺癌中的可重复性
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